SCHEMBL4574654

SCHEMBL4574654

CCOCCOCCOCC.O=C(O)C1CCC(C(=O)O)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ALDH1A1 P00352 2/20 0.45
PLG P00747 1/20 0.43
PLAT P00750 1/20 0.43
LMNA P02545 1/20 0.43
EPHX2 P34913 5/20 0.41
THRB P10828 1/20 0.39
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38
GABRA4 P48169 1/20 0.38
GABRE P78334 1/20 0.38
PMP22 Q01453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28658462 1.00 TSHR (0.45) TSHRALDH1A1PLGPLATLMNA
SCHEMBL15663011 0.98 TSHR (0.46) TSHRALDH1A1PLGPLATLMNA
SCHEMBL4574844 0.89 ALDH1A1 (0.46) TSHRALDH1A1PLGPLATLMNA
SCHEMBL19469312 0.86 PLG (0.39) TSHRALDH1A1PLGPLATLMNA
SCHEMBL3819856 0.84 PLG (0.47) TSHRALDH1A1PLGPLATLMNA
SCHEMBL11848105 0.79 ALDH1A1 (0.52) TSHRALDH1A1EPHX2THRBPPM1B
SCHEMBL849225 0.79 PLG (0.50) TSHRALDH1A1PLGPLATLMNA
SCHEMBL5656419 0.79 ALDH1A1 (0.52) TSHRALDH1A1EPHX2THRBPPM1B
SCHEMBL14932056 0.79 PLG (0.50) TSHRALDH1A1PLGPLATLMNA
SCHEMBL17592437 0.79 PLG (0.50) TSHRALDH1A1PLGPLATLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108450-A1 COSMETIC COMPOSITION FOR ENHANCING SKIN ABSORPTION AND FORMULATION STABILITY CELLTEM BIO INC. (KR) 2026-04-23 US claimed
US-20230381094-A1 Cosmetic Composition with Skin Microbiome-Friendly Properties LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2023-11-30 US claimed
WO-2023063100-A1 COSMETIC COMPOSITION 株式会社 資生堂 2023-04-20 WO claimed
US-20230021127-A1 STABLE COMPOSITION COMPRISING COMBINATION OF CINNAMIC ACID DERIVATIVES WITH SPECIFIC INGREDIENTS L'OREAL (FR) 2023-01-19 US claimed
EP-4076681-A1 STABLE COMPOSITION COMPRISING COMBINATION OF CINNAMIC ACID DERIVATIVES WITH SPECIFIC INGREDIENTS L'OREAL (FR) 2022-10-26 EP claimed
CN-114786782-A Stable composition comprising cinnamic acid derivatives in combination with specific ingredients 莱雅公司 2022-07-22 CN claimed
WO-2021125070-A1 STABLE COMPOSITION COMPRISING COMBINATION OF CINNAMIC ACID DERIVATIVES WITH SPECIFIC INGREDIENTS L'OREAL (FR) 2021-06-24 WO claimed
WO-2020122088-A1 COMPOSITION WITH LESS ODOR L'OREAL (FR) 2020-06-18 WO claimed
US-20190175457-A1 THREE-DIMENSIONAL MOLDING TYPE POWDER MAKEUP COSMETIC COMPOSITION COSON CO., LTD (KR) 2019-06-13 US claimed
US-10124030-B2 Skincare preparations KARYNG, LLC (US) 2018-11-13 US claimed
US-20170304371-A1 SKINCARE PREPARATIONS KARYNG, LLC 2017-10-26 US claimed
WO-2008156327-A2 LIPID HAVING SPECIFIC FUNCTIONAL GROUP AND PERSONAL CARE COMPOSITION COMPRISING THE LIPID LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2008-12-24 WO claimed
US-20260108450-A1 COSMETIC COMPOSITION FOR ENHANCING SKIN ABSORPTION AND FORMULATION STABILITY CELLTEM BIO INC. (KR) 2026-04-23 US disclosed
EP-3960246-B1 HIGH VISCOSITY O/W EMULSION COMPOSITION CONTAINING ADENOSINE PHOSPHATE OTSUKA PHARMA CO LTD (JP) 2026-04-22 EP disclosed
EP-4729513-A1 A-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF Nanjing Chempion Biotechnology Co., Ltd. (CN) 2026-04-22 EP disclosed
US-20250387312-A1 COSMETIC FORMULATIONS COMPRISING A BIOPOLYMER 11584022 CANADA INC. (CA) 2025-12-25 US disclosed
US-20170071848-A1 Skin Care Compositions MELALEUCA, INC. 2017-03-16 US disclosed
US-20140227217-A1 COSMETIC COMPOSITION AND COSMETIC Rhe Nisshin OilliO Group, Ltd. (JP) 2014-08-14 US disclosed
EP-2762129-A1 COSMETIC COMPOSITION AND COSMETIC The Nisshin Oillio Group, Ltd. (JP) 2014-08-06 EP disclosed
WO-2008156327-A2 LIPID HAVING SPECIFIC FUNCTIONAL GROUP AND PERSONAL CARE COMPOSITION COMPRISING THE LIPID LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2008-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250387312-A1 COSMETIC FORMULATIONS COMPRISING A BIOPOLYMER COL2A1, COL1A1, COL14A1 TSHR 4088/4885ALDH1A1 1581/4885PLG 408/4885
US-20260108450-A1 COSMETIC COMPOSITION FOR ENHANCING SKIN ABSORPTION AND FORMULATION STABILITY CERT1, SIRT1, ASAH2 TSHR 4528/4885ALDH1A1 1647/4885PLG 531/4885
US-20170304371-A1 SKINCARE PREPARATIONS COL14A1, COL1A1, COL2A1 TSHR 4624/4885ALDH1A1 3423/4885PLG 305/4885
US-10124030-B2 Skincare preparations COL14A1, COL1A1, COL2A1 TSHR 4624/4885ALDH1A1 3423/4885PLG 305/4885
US-20230021127-A1 STABLE COMPOSITION COMPRISING COMBINATION OF CINNAMIC ACID DERIVATIVES WITH SPECIFIC INGREDIENTS NQO1, ALOX5, LPO TSHR 4873/4885ALDH1A1 75/4885PLG 2644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.