Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574937 | 0.81 | ALDH1A1 (0.33) | ALDH1A1KDM4EHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL4574357 | 0.80 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10SMN1; SMN2GAA | |
| SCHEMBL5563484 | 0.65 | KMT2A (0.39) | ALDH1A1KDM4EHSD17B10SMN1; SMN2GAA | |
| Iodide SCHEMBL5323160 | 0.64 | KMT2A (0.38) | ALDH1A1KDM4EHSD17B10SMN1; SMN2GAA | |
| Dimethylamine SCHEMBL5563488 | 0.63 | ALOX15 (0.40) | ALDH1A1KDM4EHSD17B10SMN1; SMN2GAA | |
| SCHEMBL4574508 | 0.61 | KDM4E (0.39) | ALDH1A1KDM4EHSD17B10SMN1; SMN2GAA | |
| SCHEMBL4734701 | 0.61 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10GAATSHR | |
| SCHEMBL5330704 | 0.60 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EHSD17B10SMN1; SMN2GAA | |
| SCHEMBL1425344 | 0.60 | NUDT1 (0.47) | ALDH1A1KDM4EHSD17B10TSHRRAB9A | |
| SCHEMBL5324400 | 0.60 | SMN1; SMN2 (0.42) | ALDH1A1KDM4EHSD17B10SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071766-A2 | SPIRO-INDENE SUBSTITUTED IMIDAZONAPHYTHYRIDINE AND PYRANOIMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF GASTRIC ACID SECRETION | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |