Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 3/20 | 0.44 |
| ▸ | CDK8 | P49336 | 3/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17777207 | 0.74 | CCNC (0.45) | CCNCCDK8RIPK1TRPA1SCD5 | |
| SCHEMBL8957415 | 0.73 | CCNC (0.46) | CCNCCDK8RIPK1SCD5 | |
| SCHEMBL28149188 | 0.72 | TRPA1 (0.53) | CCNCCDK8RIPK1TRPA1SCD5 | |
| SCHEMBL11436917 | 0.72 | RIPK1 (0.60) | RIPK1SCD5 | |
| Hydrochloric Acid SCHEMBL16610587 | 0.72 | MAOA (0.46) | RIPK1MAOB | |
| Hydrochloric Acid SCHEMBL16610762 | 0.72 | MAOA (0.46) | RIPK1MAOB | |
| SCHEMBL5197715 | 0.72 | CCNC (0.53) | CCNCCDK8RIPK1TRPA1SCD5 | |
| SCHEMBL30964008 | 0.72 | SPHK2 (0.43) | RIPK1 | |
| SCHEMBL28170397 | 0.71 | RIPK1 (0.55) | RIPK1SCD5 | |
| SCHEMBL24367553 | 0.70 | CCNC (0.51) | CCNCCDK8RIPK1TRPA1SCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055959-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS N.V. (BE) | 2008-05-15 | — | — | WO | disclosed |