Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820403 | 0.79 | PDE4B (0.38) | SQORBACE1PDE4BALDH1A1MAPT | |
| SCHEMBL456629 | 0.79 | SQOR (0.39) | SQORCYP2A6BACE1PDE4BALDH1A1 | |
| SCHEMBL458401 | 0.78 | SQOR (0.34) | SQORBACE1PDE4BALDH1A1MAPT | |
| SCHEMBL455612 | 0.78 | ALDH1A1 (0.38) | SQORBACE1PDE4BALDH1A1MAPT | |
| SCHEMBL21331773 | 0.76 | BACE1 (0.42) | SQORBACE1PDE4BALDH1A1MAPT | |
| SCHEMBL6206554 | 0.75 | CYP2A6 (0.41) | SQORCYP2A6CTRCBACE1ALDH1A1 | |
| SCHEMBL456350 | 0.74 | CYP2A6 (0.44) | CYP2A6CTRCBACE1ALDH1A1HTT | |
| SCHEMBL457181 | 0.73 | ADRB2 (0.33) | SQORBACE1PDE4BALDH1A1MAPT | |
| SCHEMBL457353 | 0.73 | PDE4D (0.33) | SQORCYP2A6BACE1PDE4BALDH1A1 | |
| SCHEMBL2347488 | 0.71 | KDM4E (0.32) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |