SCHEMBL4577774

SCHEMBL4577774

COC(=O)[C@@H](N)CSC(=O)[C@@H](N)CCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 2/20 0.44
GRM8 O00222 1/20 0.44
GRM6 O15303 1/20 0.44
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GSR P00390 1/20 0.44
CYP1A2 P05177 1/20 0.44
GRIK1 P39086 1/20 0.44
GRM5 P41594 1/20 0.44
GRIA1 P42261 1/20 0.44
GRIA2 P42262 1/20 0.44
GRIA3 P42263 1/20 0.44
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
GRIA4 P48058 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIK2 Q13002 1/20 0.44
GRIK3 Q13003 1/20 0.44
GRIN2B Q13224 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137711 0.86 NOD1 (0.44) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL338792 0.82 SLC1A1 (0.58) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL562202 0.82 SLC1A1 (0.58) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL6146852 0.82 SLC1A1 (0.58) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL210492 0.81 GRM8 (0.63) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL29240006 0.81 GRM8 (0.63) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL15420878 0.81 GRM8 (0.63) SLC1A1GRM8GRM6GRIN2DGRIN3B
Hydrochloric Acid SCHEMBL3174569 0.81 SLC1A1 (0.56) SLC1A1GRM8GRM6GRIN2DGRIN3B
Hydrochloric Acid SCHEMBL7445184 0.81 SLC1A1 (0.56) SLC1A1GRM8GRM6GRIN2DGRIN3B
SCHEMBL27805447 0.81 SLC1A1 (0.56) SLC1A1GRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1026516-A None JP disclosed
US-20080182803-A1 extract from Cassia or Senna plants comprises rubrofusarin gentiobioside with egg white, egg membrane, milk whey, yeast/vegetable proteins, soy bean, L-cysteine, L-methionine, and vitamin C; synergistic; intracellular biosynthesis of glutathione stimulator; liver, brain, vision, or immune disorders SUNTORY LIMITED 2008-07-31 US disclosed
US-20060110474-A1 Rubrofusarin glycoside-containing composition SUNTORY LIMITED (JP) 2006-05-25 US disclosed
EP-1552838-A1 RUBROFUSARIN GLYCOSIDE-CONTAINING COMPOSITION SUNTORY LIMITED (JP) 2005-07-13 EP disclosed
US-5624955-A Compounds that enhance the concentration of glutathione in tissues REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1997-04-29 US disclosed
EP-0276317-B1 GAMMA-L-GLUTAMYL-L-CYSTEINE ETHYL ESTER AND DRUG CONTAINING IT AS EFFECTIVE INGREDIENT TEIJIN LIMITED (JP) 1993-03-17 EP disclosed
US-4927808-A GLUTATHIONE LEVELS IN TISSUES TEIJIN LIMITED (JP) 1990-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060110474-A1 Rubrofusarin glycoside-containing composition GSTP1, GLS, MGST3 SLC1A1 821/4885GRM8 1157/4885GRM6 718/4885
US-20080182803-A1 extract from Cassia or Senna plants comprises rubrofusarin gentiobioside with egg white, egg membrane, milk whey, yeast/vegetable proteins, soy bean, L-cysteine, L-methionine, and vitamin C; synergistic; intracellular biosynthesis of glutathione stimulator; liver, brain, vision, or immune disorders GSS, GSTP1, GSTM2 SLC1A1 1988/4885GRM8 1436/4885GRM6 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.