Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D known ✓ | O15399 | 1/20 | 0.56 |
| ▸ | GRIN3B known ✓ | O60391 | 1/20 | 0.56 |
| ▸ | GRIN1 known ✓ | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A known ✓ | Q12879 | 1/20 | 0.56 |
| ▸ | GRIN2B known ✓ | Q13224 | 1/20 | 0.56 |
| ▸ | GRIN2C known ✓ | Q14957 | 1/20 | 0.56 |
| ▸ | GRIN3A known ✓ | Q8TCU5 | 1/20 | 0.56 |
| ▸ | GABRP known ✓ | O00591 | 2/20 | 0.50 |
| ▸ | GABRD known ✓ | O14764 | 2/20 | 0.50 |
| ▸ | GABRA1 known ✓ | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 known ✓ | P18505 | 2/20 | 0.50 |
| ▸ | GABRG2 known ✓ | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 known ✓ | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 known ✓ | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 known ✓ | P34903 | 2/20 | 0.50 |
| ▸ | GABRA2 known ✓ | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 known ✓ | P47870 | 2/20 | 0.50 |
| ▸ | GABRA4 known ✓ | P48169 | 2/20 | 0.50 |
| ▸ | GABRE known ✓ | P78334 | 2/20 | 0.50 |
| ▸ | GABRA6 known ✓ | Q16445 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7445184 | 1.00 | SLC1A1 (0.56) | SLC1A1GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL6146852 | 0.98 | SLC1A1 (0.58) | SLC1A1GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL562202 | 0.98 | SLC1A1 (0.58) | SLC1A1GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL338792 | 0.98 | SLC1A1 (0.58) | SLC1A1GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL27805447 | 0.96 | SLC1A1 (0.56) | SLC1A1GRM8GRM6GRIN2DGRIN3B | |
| Glutamic Acid SCHEMBL1930763 | 0.92 | SLC1A1 (0.69) | SLC1A1GRM8GRM6GRIN2DGRIN3B | |
| Phosphoric Acid SCHEMBL28734817 | 0.90 | GRM8 (0.50) | SLC1A1GRM8GRM6GRIN2DGRIN3B | |
| Sulfuric Acid SCHEMBL28734792 | 0.90 | SLC1A1 (0.50) | SLC1A1GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL21268583 | 0.89 | SLC1A1 (0.48) | SLC1A1GRM8GRM6GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL31318442 | 0.88 | ENPEP (0.46) | SLC1A1GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290360-A | Synthetic method of organic light response probe HBT-CN based on ESIPT effect, obtained probe and application thereof | 临沂大学 | 2024-07-05 | — | — | CN | claimed |
| CN-114453022-A | Acid catalyst for reducing acid value of high-acid-value oil, preparation method, recovery method and application thereof | 大连医诺生物股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-111218130-A | Modification method for obtaining metal ion complexing performance by solid surface modification | 天津科技大学 | 2020-06-02 | — | — | CN | claimed |
| CN-103131004-A | Polymethylglutamate and preparation method thereof | BIOCHEMICAL ENG COLLEGE BJ | 2013-06-05 | — | — | CN | claimed |
| CN-118290360-A | Synthetic method of organic light response probe HBT-CN based on ESIPT effect, obtained probe and application thereof | 临沂大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-112830884-B | Salvianic acid a derivative, preparation method and medical application thereof | 深圳市高盈医药科技开发有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-116731097-A | Amino acid methyl ester substituted uridine and derivatives thereof, preparation method and application thereof | 河南省科学院高新技术研究中心 | 2023-09-12 | — | — | CN | disclosed |
| CN-114751863-A | Terestacin derivative, preparation method thereof and application of Terestacin derivative in preparation of low-oxygen factor inhibitor | 中国科学院南海海洋研究所 | 2022-07-15 | — | — | CN | disclosed |
| CN-114453022-A | Acid catalyst for reducing acid value of high-acid-value oil, preparation method, recovery method and application thereof | 大连医诺生物股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-110408584-B | Left-handed chiral nanogel cell scaffold material and preparation method thereof | 上海交通大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-111218130-A | Modification method for obtaining metal ion complexing performance by solid surface modification | 天津科技大学 | 2020-06-02 | — | — | CN | disclosed |
| CN-105001119-B | A kind of preparation method of aldehyde perfume derivative and the application in cigarette blending | 湖北中烟工业有限责任公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-1671654-A | Gelling agent | APPLIED NANOSYSTEMS BV (NL) | 2005-09-21 | — | — | CN | disclosed |
| EP-1506168-A2 | GELLING AGENTS | Applied NanoSystems B.V. (NL) | 2005-02-16 | — | — | EP | disclosed |
| EP-1490028-A1 | DELIVERY OF A SUBSTANCE TO A PRE-DETERMINED SITE | Applied NanoSystems B.V. (NL) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003097587-A2 | GELLING AGENTS | APPLIED NANOSYSTEMS B.V. (NL) | 2003-11-27 | — | — | WO | disclosed |
| WO-2003084508-A1 | DELIVERY OF A SUBSTANCE TO A PRE-DETERMINED SITE | APPLIED NANOSYSTEMS B.V. (NL) | 2003-10-16 | — | — | WO | disclosed |
| EP-1001971-A1 | DIPEPTIDE AND RELATED COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006432-A1 | DIPEPTIDE AND RELATED COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0343801-A2 | N-(5,6,7,8-tetrahydropyrido(2,3-D)pyrimidin-6-yl-alkanoyl)-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-11-29 | — | — | EP | disclosed |