Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | FABP2 | P12104 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457978 | 0.86 | TP53 (0.32) | ADORA3ADORA2AADORA1HPGDMAPT | |
| SCHEMBL458760 | 0.81 | ESR2 (0.34) | ADORA3ADORA2AADORA1HPGDSMN1; SMN2 | |
| SCHEMBL457181 | 0.80 | ADRB2 (0.33) | ADORA3ADORA2AADORA1MAPTALDH1A1 | |
| SCHEMBL456773 | 0.79 | CYP2A6 (0.35) | ADORA3ADORA2AADORA1HPGDSMN1; SMN2 | |
| SCHEMBL457437 | 0.79 | ADORA3 (0.33) | ADORA3ADORA2AADORA1HPGDSMN1; SMN2 | |
| SCHEMBL14675940 | 0.72 | ESR2 (0.38) | HPGDMAPTALDH1A1HSD17B10PTGS1 | |
| SCHEMBL10428951 | 0.71 | BACE1 (0.36) | HPGDMAPTALDH1A1HSD17B10PTGS1 | |
| SCHEMBL4155256 | 0.71 | PSMB5 (0.38) | SOAT1TSHRPSMB5 | |
| SCHEMBL456919 | 0.68 | ALDH1A1 (0.41) | ADORA1HPGDMAPTALDH1A1HSD17B10 | |
| SCHEMBL7814278 | 0.68 | CYP2A6 (0.41) | HPGDMAPTALDH1A1HSD17B10PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |