SCHEMBL4578764

SCHEMBL4578764

C=C(Cc1ccc(C(C)(C)C)cc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 5/20 0.50
EPHX2 P34913 2/20 0.50
RXRA P19793 2/20 0.47
RXRB P28702 2/20 0.47
RXRG P48443 1/20 0.47
ALDH1A1 P00352 1/20 0.46
ESRRG P62508 3/20 0.45
ESRRB O95718 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
SLC13A5 Q86YT5 2/20 0.44
NR4A2 P43354 1/20 0.44
ERCC5 P28715 1/20 0.43
FEN1 P39748 1/20 0.43
NLRP3 Q96P20 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4797444 0.95 RXRA (0.55) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL16162260 0.84 ALDH1A1 (0.47) ALDH1A1ESRRGSMN1; SMN2LMNA
SCHEMBL3426193 0.84 CA2 (0.46) ALDH1A1LMNA
SCHEMBL4903762 0.83 SHBG (0.49) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL15301196 0.82 NR1H4 (0.52) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL11242547 0.81 PIK3CA (0.49) EPHX2RXRARXRBRXRGNLRP3
SCHEMBL6775096 0.81 NR1H4 (0.53) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL28272620 0.81 LMNA (0.51) NR1H4EPHX2ALDH1A1ESRRGESRRB
SCHEMBL840854 0.80 NR1H4 (0.70) NR1H4EPHX2RXRARXRBRXRG
SCHEMBL6442701 0.79 ALDH1A1 (0.52) RXRARXRBALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7368544-B2 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2008-05-06 US disclosed
US-7314698-B2 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2008-01-01 US disclosed
US-7090957-B2 Polymerizable composition and planographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. (JP) 2006-08-15 US disclosed
US-20060135742-A1 Polymerizable composition and planographic printng plate precursor using the same FUJI PHOTO FILM CO., LTD. 2006-06-22 US disclosed
US-20060127809-A1 Polymerizable composition and planographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. 2006-06-15 US disclosed
US-20040062939-A1 Polymerizable composition and planogaphic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. 2004-04-01 US disclosed
EP-1400851-A2 Polymerizable composition and planographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. (JP) 2004-03-24 EP disclosed