SCHEMBL4580643

SCHEMBL4580643

O=C(O)c1cccc(C(=O)OC2(c3ccccc3)CCCCC2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.41
KMO O15229 2/20 0.40
AKR1C1 Q04828 1/20 0.39
POLB P06746 1/20 0.38
ALDH1A1 P00352 3/20 0.38
GAA P10253 2/20 0.38
KMT2A Q03164 2/20 0.38
HDAC4 P56524 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 3/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
HIF1A Q16665 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA6 P23280 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4580640 0.96 AKR1C1 (0.42) AKR1C1ALDH1A1GAAKMT2AHDAC4
SCHEMBL27593585 0.88 LMNA (0.48) AKR1C1KMT2AHDAC4MEN1LMNA
SCHEMBL4580283 0.87 AKR1C1 (0.42) AKR1C1KMT2AHDAC4MEN1LMNA
SCHEMBL4580279 0.85 AKR1C1 (0.46) AKR1C1POLBALDH1A1KMT2AHDAC4
SCHEMBL10687586 0.83 LMNA (0.50) AKR1C1POLBALDH1A1KMT2AHDAC4
SCHEMBL4580673 0.79 AKR1C1 (0.46) AKR1C1ALDH1A1KMT2AHDAC4MEN1
SCHEMBL14062595 0.78 L3MBTL1 (0.43) AKR1C1POLBALDH1A1KMT2AKDM4E
SCHEMBL4580676 0.78 ALDH1A1 (0.44) AKR1C3AKR1C1ALDH1A1KMT2AHDAC4
SCHEMBL28146980 0.78 KDM4E (0.41) AKR1C3KMOPOLBALDH1A1GAA
SCHEMBL27516395 0.77 CES2 (0.45) ALDH1A1KMT2AKDM4EMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7407686-B2 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION (JP) 2008-08-05 US disclosed
US-20060062936-A1 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION 2006-03-23 US disclosed
US-20030170482-A1 Optical film, polarizing plate and display device utilizing the film, and production method of optical film KONICA CORPORATION (JP) 2003-09-11 US disclosed