Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584263 | 0.84 | NR3C1 (0.34) | ALDH1A1KDM4ENR3C1 | |
| SCHEMBL1961669 | 0.82 | MCHR1 (0.33) | LMNAMAPK1TSHRCYP1A2CYP3A4 | |
| SCHEMBL12479130 | 0.80 | CA12 (0.33) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10035244 | 0.79 | HTR1A (0.33) | ALDH1A1HSD17B10SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL14570902 | 0.78 | NR3C1 (0.32) | ABCB1ALDH1A1NR3C1 | |
| SCHEMBL1965136 | 0.77 | FPR1 (0.33) | LMNAALDH1A1MAPK1TSHRHSD17B10 | |
| SCHEMBL10035238 | 0.75 | — | — | |
| SCHEMBL1965015 | 0.74 | SYK (0.32) | HPGD | |
| SCHEMBL4619309 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPK1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL14570900 | 0.74 | SYK (0.34) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1980555-A1 | 4-(3-aminobenzoyl)-1.3-dimethyl pyrazoles and their application as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2008-10-15 | — | — | EP | disclosed |