SCHEMBL14570902

SCHEMBL14570902

COCCNc1c(S(C)(=O)=O)ccc(C(=O)c2c(C)nn(C)c2OC)c1CSC

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.32
SYK P43405 1/20 0.31
ABCB1 P08183 2/20 0.31
HTR1A P08908 1/20 0.31
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5549072 0.91 NR3C1 (0.32) NR3C1ALDH1A1
SCHEMBL14570900 0.80 SYK (0.34) NR3C1SYK
SCHEMBL14570907 0.80 SYK (0.32) SYKALDH1A1
SCHEMBL5549100 0.79 MAPK1 (0.36) ALDH1A1
SCHEMBL4584263 0.78 NR3C1 (0.34) NR3C1SYKHTR1AADRA1DADRA1A
SCHEMBL4583463 0.78 ABCB1 (0.37) NR3C1ABCB1ALDH1A1
SCHEMBL14570909 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL10035244 0.73 HTR1A (0.33) NR3C1HTR1AADRA1DADRA1AADRA1B
SCHEMBL10035246 0.71 NR3C1 (0.36) NR3C1HTR1AADRA1DADRA1AADRA1B
SCHEMBL1965136 0.71 FPR1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189679-B2 Herbicidal 3-amino-2-thiomethylbenzoylpyrazoles BAYER CROPSCIENCE GMBH (DE) 2007-03-13 US disclosed