Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 6/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585393 | 0.89 | CCR5 (0.53) | CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL4586423 | 0.87 | CCR5 (0.41) | CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL4245439 | 0.84 | CCR5 (0.53) | CCR5UBE2MDCUN1D1 | |
| SCHEMBL4237093 | 0.84 | CCR5 (0.53) | CCR5UBE2MDCUN1D1 | |
| SCHEMBL4585402 | 0.83 | CCR5 (0.41) | CCR5ALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL4587616 | 0.82 | CCR5 (0.42) | CCR5OPRM1OPRD1OPRK1SLC6A4 | |
| SCHEMBL4237091 | 0.80 | CCR5 (0.52) | CCR5PDK1UBE2MDCUN1D1 | |
| SCHEMBL4245437 | 0.80 | CCR5 (0.52) | CCR5PDK1UBE2MDCUN1D1 | |
| SCHEMBL4585487 | 0.78 | OPRM1 (0.41) | CCR5ALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL4586731 | 0.75 | OPRM1 (0.53) | CCR5OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |