Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584322 | 0.84 | L3MBTL1 (0.49) | KMT2AHDAC1HDAC6L3MBTL1HDAC3 | |
| SCHEMBL6952927 | 0.81 | ALDH1A1 (0.47) | KMT2AHDAC1HDAC6L3MBTL1HDAC3 | |
| SCHEMBL5703870 | 0.80 | HDAC3 (0.42) | KMT2AHDAC1L3MBTL1HDAC3HDAC2 | |
| SCHEMBL6378052 | 0.80 | ALDH1A1 (0.47) | KMT2AHDAC1HDAC6L3MBTL1HDAC3 | |
| SCHEMBL5703802 | 0.79 | KMT2A (0.48) | KMT2AHDAC1HDAC6L3MBTL1HDAC3 | |
| SCHEMBL4468550 | 0.79 | HDAC1 (0.47) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL2593275 | 0.78 | CRHBP (0.54) | KMT2AHDAC1HDAC6L3MBTL1HDAC3 | |
| SCHEMBL6377823 | 0.77 | ALDH1A1 (0.48) | KMT2AHDAC1HDAC6L3MBTL1HDAC3 | |
| SCHEMBL2595558 | 0.77 | KMT2A (0.47) | KMT2AHDAC1HDAC6L3MBTL1HDAC3 | |
| SCHEMBL6378384 | 0.77 | ALDH1A1 (0.48) | KMT2AHDAC1HDAC6L3MBTL1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417060-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20050137236-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137236-A1 | Aminoalcohol derivatives | GPR39, PRMT9, CHRM2 | KMT2A 630/4885HDAC1 1357/4885HDAC6 793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.