Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 5/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585716 | 0.76 | L3MBTL1 (0.42) | L3MBTL1MAPTHTTLTA4HKDM4E | |
| SCHEMBL4586745 | 0.75 | L3MBTL1 (0.40) | L3MBTL1MAPTLMNAHTTKDM4E | |
| SCHEMBL14810207 | 0.70 | HDAC8 (0.40) | L3MBTL1LMNAHTTKDM4E | |
| SCHEMBL7980416 | 0.69 | L3MBTL1 (0.58) | L3MBTL1MAPTMDM2HTTKDM4E | |
| SCHEMBL34467479 | 0.68 | HPGD (0.43) | L3MBTL1MAPTLMNAHTT | |
| SCHEMBL27754512 | 0.67 | L3MBTL1 (0.46) | L3MBTL1MAPTKAT2B | |
| SCHEMBL7977632 | 0.66 | HPGD (0.50) | L3MBTL1MAPTLMNAHTTKDM4E | |
| SCHEMBL6810549 | 0.66 | L3MBTL1 (0.57) | L3MBTL1MAPTKDM4EPOLB | |
| SCHEMBL7499557 | 0.65 | L3MBTL1 (0.50) | L3MBTL1MAPTMDM2KAT2BPOLB | |
| SCHEMBL7543969 | 0.65 | EGFR (0.41) | L3MBTL1MAPTLTA4HKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455266-B2 | Multi-stack ferroelectric polymer memory | SONY CORPORATION (JP) | 2013-06-04 | — | — | US | disclosed |
| EP-1581213-A4 | 3,5-DISUBSTITUTED- 1,2,4 -OXADIAZOLES AND ANALOGS AS AC TIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA INC (US) | 2008-11-19 | — | — | EP | disclosed |
| US-20080273367-A1 | MULTI-STACK FERROELECTRIC POLYMER MEMORY DEVICE AND METHOD FOR MANUFACTURING SAME | SONY CORPORATION (JP) | 2008-11-06 | — | — | US | disclosed |
| US-7317029-B2 | 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7144876-B2 | 3,5-Disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2006-12-05 | — | — | US | disclosed |
| EP-1581213-A1 | 3,5-DISUBSTITUTED- 1,2,4 -OXADIAZOLES AND ANALOGS AS AC TIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004058253-A1 | 3,5-DISUBSTITUTED-[1,2,4]-OXADIAZOLES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040127521-A1 | 3,5-Disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127521-A1 | 3,5-Disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP1, CASP3, CASP2 | L3MBTL1 576/4885MAPT 4540/4885TMPRSS15 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.