Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.54 |
| ▸ | CASR | P41180 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21131169 | 0.91 | ADRB2 (0.54) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL27536284 | 0.88 | HPGD (0.53) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| Carbamic Acid SCHEMBL7402351 | 0.84 | ITGB3 (0.51) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL9057742 | 0.83 | AKR1C3 (0.49) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL873032 | 0.82 | AKR1C3 (0.61) | NPC1RAB9ASMN1; SMN2AKR1C3NR1H4 | |
| SCHEMBL27635203 | 0.80 | AKR1C3 (0.63) | NPC1RAB9AAKR1C3CASRPPARA | |
| SCHEMBL6325442 | 0.79 | AKR1C3 (0.58) | SMN1; SMN2AKR1C3NR1H4 | |
| SCHEMBL7609012 | 0.79 | AKR1C3 (0.61) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL497784 | 0.78 | AKR1C3 (0.65) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL26733447 | 0.78 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10322998-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-18 | — | — | US | disclosed |
| US-20120021530-A1 | HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2012-01-26 | — | — | US | disclosed |
| US-7858737-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-12-28 | — | — | US | disclosed |
| US-20040116654-A1 | Heterogeneous foldamers containing alpha, beta, and/or gamma-amino acids | NATIONAL SCIENCE FOUNDATION | 2004-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10322998-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | DNPEP, PRKCSH, BCAT1 | NPC1 4635/4885RAB9A 3067/4885SMN1; SMN2 4002/4885 |
| US-20120021530-A1 | HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS | DNPEP, PRKCSH, YWHAZ | NPC1 4725/4885RAB9A 3084/4885SMN1; SMN2 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.