Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952253 | 0.79 | CA2 (0.40) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL717061 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL6346979 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL8099528 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL536089 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL1861089 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1KIF11MAPT | |
| SCHEMBL179312 | 0.76 | TSHR (0.50) | ALDH1A1TSHRTDP1CA2 | |
| Ethane SCHEMBL2153712 | 0.74 | TSHR (0.48) | ALDH1A1TSHRTDP1CA2 | |
| Ethylene SCHEMBL28248107 | 0.73 | TSHR (0.46) | ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL5475379 | 0.73 | TSHR (0.35) | ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7408060-B2 | Nonsteroidal progesterone receptor modulators | SCHERING AG (DE) | 2008-08-05 | — | — | US | claimed |
| EP-1902049-A2 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-03-26 | — | — | EP | claimed |
| EP-1899315-A1 | BENZOFURANONE DERIVATIVES AS NONSTEROIDAL PROGESTERONE RECEPTOR MODULATORS | Schering Aktiengesellschaft (DE) | 2008-03-19 | — | — | EP | claimed |
| US-20070142464-A1 | Nonsteroidal progesterone receptor modulators | SCHERING AG (DE) | 2007-06-21 | — | — | US | claimed |
| US-20070010514-A1 | Non-steroidal progesterone receptor modulators | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-01-11 | — | — | US | claimed |
| WO-2006136462-A1 | BENZOFURANONE DERIVATIVES AS NONSTEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | claimed |
| WO-2006136461-A2 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | claimed |
| US-8372871-B2 | Histidinol dehydrogenase inhibitors, and use thereof as medicaments | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-02-12 | — | — | US | disclosed |
| US-20120129907-A1 | HISTIDINOL DEHYDROGENASE INHIBITORS, AND USE THEREOF AS MEDICAMENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-05-24 | — | — | US | disclosed |
| US-5284821-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| US-5256633-A | Applying pre or postemergence | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| US-5244867-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129907-A1 | HISTIDINOL DEHYDROGENASE INHIBITORS, AND USE THEREOF AS MEDICAMENTS | MDH2, MDH1, G6PD | ALDH1A1 110/4885TSHR 3806/4885TDP1 1599/4885 |
| US-20070010514-A1 | Non-steroidal progesterone receptor modulators | PGR, PGRMC1, CYP19A1 | ALDH1A1 1444/4885TSHR 123/4885TDP1 3156/4885 |
| US-20070142464-A1 | Nonsteroidal progesterone receptor modulators | PGR, PGRMC1, PGRMC2 | ALDH1A1 1023/4885TSHR 225/4885TDP1 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.