Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 5/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | IL18 | Q14116 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544256 | 0.96 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CYP2A6ARPARP15 | |
| SCHEMBL459019 | 0.85 | ALDH1A1 (0.73) | ALDH1A1CYP2A6ARPARP15PARP10 | |
| SCHEMBL29582194 | 0.85 | PARP15 (0.57) | ALDH1A1SMN1; SMN2CYP2A6ARPARP15 | |
| SCHEMBL31070296 | 0.83 | AR (0.63) | ALDH1A1CYP2A6ARPARP15PARP10 | |
| SCHEMBL921433 | 0.83 | AR (0.63) | ALDH1A1CYP2A6ARPARP15PARP10 | |
| SCHEMBL8852392 | 0.82 | PARP15 (0.63) | ALDH1A1SMN1; SMN2CYP2A6ARPARP15 | |
| SCHEMBL9352887 | 0.82 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL7041250 | 0.82 | PARP15 (0.63) | ALDH1A1SMN1; SMN2CYP2A6ARPARP15 | |
| SCHEMBL924026 | 0.81 | AR (0.55) | ALDH1A1SMN1; SMN2CYP2A6ARPARP15 | |
| SCHEMBL31070291 | 0.80 | ALDH1A1 (0.64) | ALDH1A1CYP2A6ARPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032261-A1 | METHOD FOR SYNTHESISING BIARYL ETHER OR BIHETEROARYL ETHER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2012-03-15 | — | — | WO | disclosed |
| US-20110009454-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20110009454-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2248423-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | Sumitomo Chemical Company, Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20100137608-A1 | POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-06-03 | — | — | US | disclosed |
| WO-2009107764-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | 住友化学株式会社 (JP) | 2009-09-03 | — | — | WO | disclosed |
| WO-2008136770-A1 | POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-11-13 | — | — | WO | disclosed |
| US-7202367-B2 | Process for arylating or vinylating or alkynating a nucleophilic compound | RHODIA CHIMIE (FR) | 2007-04-10 | — | — | US | disclosed |
| US-7202367-B2 | Process for arylating or vinylating or alkynating a nucleophilic compound | RHODIA CHIMIE (FR) | 2007-04-10 | — | — | US | disclosed |
| US-20050234239-A1 | Method of forming a carbon-carbon or carbon-heteroatom linkage | SHASUN PHARMA SOLUTIONS, INC. | 2005-10-20 | — | — | US | disclosed |
| US-20030236413-A1 | Catalysis in presence of a metallic element, an imine ligand and nitrogen compound as chelating compound, forming a chemical intermediates in the agrochemical and pharmaceutical fields | SHASUN PHARMA SOLUTIONS, INC. | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234239-A1 | Method of forming a carbon-carbon or carbon-heteroatom linkage | AOC1, AOC3, NUDT1 | ALDH1A1 436/4885SMN1; SMN2 3694/4885CYP2A6 140/4885 |
| US-20030236413-A1 | Catalysis in presence of a metallic element, an imine ligand and nitrogen compound as chelating compound, forming a chemical intermediates in the agrochemical and pharmaceutical fields | ALK, INMT, ACHE | ALDH1A1 559/4885SMN1; SMN2 661/4885CYP2A6 123/4885 |
| US-20100137608-A1 | POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS | SCO2, CYCS, NCLN | ALDH1A1 4680/4885SMN1; SMN2 1942/4885CYP2A6 3554/4885 |
| US-20110009454-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | WIZ, TST, NAT1 | ALDH1A1 2743/4885SMN1; SMN2 4796/4885CYP2A6 3797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.