Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590582 | 0.82 | PLA2G4A (0.42) | RBP4SMYD3KDM5AKDM4CKDM5B | |
| SCHEMBL1051399 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL709418 | 0.68 | KDM5A (0.38) | RBP4SMYD3KDM5A | |
| SCHEMBL3688462 | 0.66 | KDM4C (0.57) | RBP4KLKB1KDM5AKDM4CKDM5B | |
| SCHEMBL3689829 | 0.64 | PLA2G4A (0.40) | RBP4SMYD3KDM5AKDM4CKDM5B | |
| SCHEMBL16690901 | 0.63 | RBP4 (0.54) | RBP4KLKB1KDM5AKDM4CKDM5B | |
| SCHEMBL4737266 | 0.63 | RBP4 (0.48) | RBP4KLKB1KDM5AKDM4CKDM5B | |
| SCHEMBL7078593 | 0.63 | KDM4C (0.48) | RBP4KLKB1KDM5AKDM4CKDM5B | |
| SCHEMBL15964744 | 0.63 | RBP4 (0.54) | RBP4KLKB1KDM5AKDM4CKDM5B | |
| SCHEMBL21361934 | 0.63 | MEN1 (0.43) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |