Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29641696 | 1.00 | KMT2A (0.44) | KMT2AMEN1CDC25BNPC1RAB9A | |
| SCHEMBL1103721 | 0.93 | MEN1 (0.44) | KMT2AMEN1CDC25BNPC1RAB9A | |
| SCHEMBL16895263 | 0.85 | DNMT1 (0.46) | KMT2AMEN1CDC25BNPC1RAB9A | |
| SCHEMBL6776178 | 0.85 | MAOA (0.56) | CDC25BNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6781932 | 0.80 | MAPT (0.40) | KMT2AMEN1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL29860296 | 0.80 | TOP1 (0.46) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12854093 | 0.78 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2MAPTESR1 | |
| SCHEMBL1649965 | 0.75 | MAOA (0.44) | KMT2AMEN1CDC25BSMN1; SMN2MAPT | |
| SCHEMBL8874682 | 0.74 | KDM4E (0.42) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL30996234 | 0.73 | KDM4E (0.36) | NPC1RAB9ASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120254-A1 | DISULFIRAM COMPOSITIONS AND TREATMENTS FOR BRAIN TUMORS | TEXAS TECH UNIVERSITY SYSTEM (US) | 2015-08-13 | — | — | WO | claimed |
| US-20250074917-A1 | Preparation and Uses of 7-Azaindenoisoquinolines | PURDUE RESEARCH FOUNDATION | 2025-03-06 | — | — | US | disclosed |
| CN-119497715-A | Preparation and application of 7-aza-indeno isoquinoline | 珀杜研究基金会 | 2025-02-21 | — | — | CN | disclosed |
| US-20240287089-A1 | Preparation and Uses of 7-Azaindenoisoquinolines | PURDUE RESEARCH FOUNDATION (US) | 2024-08-29 | — | — | US | disclosed |
| US-20240239730-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-07-18 | — | — | US | disclosed |
| EP-4389765-A2 | METHODS OF PERMEABILIZING THE BLOOD BRAIN BARRIER | University of Southern California (US) | 2024-06-26 | — | — | EP | disclosed |
| US-20240197891-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-06-20 | — | — | US | disclosed |
| EP-4374929-A2 | METHODS AND DEVICES FOR USING ISOPERILLYL ALCOHOL | University of Southern California (US) | 2024-05-29 | — | — | EP | disclosed |
| US-11970436-B2 | Pharmaceutical compositions comprising monoterpenes | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-04-30 | — | — | US | disclosed |
| US-11952415-B2 | Scaffold proteins | AVACTA LIFE SCIENCES LIMITED (GB) | 2024-04-09 | — | — | US | disclosed |
| WO-2008088854-A2 | GENETIC MARKERS FOR PREDICTING RESPONSIVENESS TO COMBINATION THERAPY | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-07-24 | — | — | WO | disclosed |
| EP-1436293-B1 | POLYCYCLIC COMPOUNDS HAVING ANTI-TUMOR ACTIVITY | HOFFMANN LA ROCHE (CH) | 2006-02-01 | — | — | EP | disclosed |
| US-20050245561-A1 | Anti-tumour polycyclic carboxamides | AUCKLAND UNISERVICES LIMITED (NZ) | 2005-11-03 | — | — | US | disclosed |
| US-6946472-B2 | Polycyclic compounds exhibiting anti-tumor activities | HOFFMAN-LA ROCHE INC. (US) | 2005-09-20 | — | — | US | disclosed |
| EP-1436293-A1 | POLYCYCLIC COMPOUNDS HAVING ANTI-TUMOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-14 | — | — | EP | disclosed |
| US-6680326-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS | HOFFMANN-LA ROCHE INC. | 2004-01-20 | — | — | US | disclosed |
| US-20030229098-A1 | Polycyclic compounds exhibiting anti-tumor activities | F.HOFFMANN-LA ROCHE AG (CH) | 2003-12-11 | — | — | US | disclosed |
| WO-2003093265-A1 | DIMERIC POLYCYCLIC COMPOUNDS FOR THE TREATMENT OF TUMORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-13 | — | — | WO | disclosed |
| US-20030073691-A1 | Polycyclic compounds | HOFFMANN-LA ROCHE INC. | 2003-04-17 | — | — | US | disclosed |
| WO-2003031444-A1 | POLYCYCLIC COMPOUNDS HAVING ANTI-TUMOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239730-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES | SQLE, DHPS, GGPS1 | KMT2A 4026/4885MEN1 53/4885CDC25B 1706/4885 |
| US-20030073691-A1 | Polycyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MCL1, PKD1 | KMT2A 1200/4885MEN1 593/4885CDC25B 447/4885 |
| US-20250074917-A1 | Preparation and Uses of 7-Azaindenoisoquinolines | MYC, MYCBP, DNMT1 | KMT2A 941/4885MEN1 314/4885CDC25B 348/4885 |
| US-20240197891-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | PLIN3, PLIN5, PLIN1 | KMT2A 4089/4885MEN1 4696/4885CDC25B 1576/4885 |
| US-11952415-B2 | Scaffold proteins | TPD52L2, Q6ZSR9, G3BP2 | KMT2A 4098/4885MEN1 3239/4885CDC25B 2061/4885 |
| US-11970436-B2 | Pharmaceutical compositions comprising monoterpenes | SQLE, DHPS, GGPS1 | KMT2A 4026/4885MEN1 53/4885CDC25B 1706/4885 |
| US-20050245561-A1 | Anti-tumour polycyclic carboxamides | MKI67, MCL1, CCNI | KMT2A 492/4885MEN1 1089/4885CDC25B 145/4885 |
| US-20030229098-A1 | Polycyclic compounds exhibiting anti-tumor activities | RB1, CCNA1, ACIN1 | KMT2A 1567/4885MEN1 999/4885CDC25B 146/4885 |
| US-20240287089-A1 | Preparation and Uses of 7-Azaindenoisoquinolines | MYC, MYCBP, DNMT1 | KMT2A 941/4885MEN1 314/4885CDC25B 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.