Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621953 | 0.75 | SMN1; SMN2 (0.49) | L3MBTL1ALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL4591323 | 0.72 | DRD2 (0.39) | L3MBTL1ALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL5619238 | 0.70 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL4102891 | 0.67 | BCHE (0.38) | L3MBTL1ALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL5222472 | 0.67 | DRD2 (0.34) | ALDH1A1SMN1; SMN2HTR1ADRD2HTR2A | |
| SCHEMBL8810859 | 0.66 | GRM2 (0.49) | L3MBTL1ALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL8807325 | 0.64 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL11264742 | 0.64 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL13525311 | 0.62 | DRD2 (0.51) | CYP1A2KDM4EHTR1ADRD2HTR2A | |
| SCHEMBL7806232 | 0.62 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1HSD17B10SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114983960-A | Pharmaceutical composition and preparation method thereof | 微研优仿医药科技(江苏)有限公司 | 2022-09-02 | — | — | CN | disclosed |
| WO-2010003702-A9 | SYNTHESIS OF PALIPERIDONE | SYNTHON B.V. (NL) | 2010-12-02 | — | — | WO | disclosed |