Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464514 | 0.84 | SLC6A2 (0.48) | OPRM1SLC6A3SLC6A4OPRL1 | |
| SCHEMBL1012743 | 0.84 | SLC6A2 (0.48) | OPRM1SLC6A3SLC6A4OPRL1 | |
| SCHEMBL15956392 | 0.81 | OPRM1 (0.46) | OPRM1SLC6A3SLC6A4OPRL1 | |
| SCHEMBL7157429 | 0.80 | OPRK1 (0.46) | OPRM1SLC6A3SLC6A4ADAM17OPRL1 | |
| SCHEMBL7744850 | 0.80 | OPRM1 (0.56) | OPRM1SLC6A3SLC6A4ADAM17 | |
| SCHEMBL7568500 | 0.79 | CYP2D6 (0.48) | OPRM1SLC6A3SLC6A4OPRL1 | |
| SCHEMBL5730907 | 0.79 | OPRM1 (0.40) | OPRM1OPRL1 | |
| SCHEMBL1012066 | 0.79 | SLC6A4 (0.43) | OPRM1SLC6A3SLC6A4 | |
| SCHEMBL3656139 | 0.79 | ALDH1A1 (0.47) | OPRM1SLC6A3SLC6A4OPRL1 | |
| SCHEMBL7160342 | 0.79 | ALDH1A1 (0.35) | SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945212-A1 | TREATMENT OF DIABETES | NEUROSEARCH A/S (DK) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007051594-A1 | TREATMENT OF DIABETES | NEUROSEARCH A/S (DK) | 2007-05-10 | — | — | WO | disclosed |