Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012742 | 0.80 | MEN1 (0.40) | MEN1KMT2AMAPT | |
| SCHEMBL11100675 | 0.75 | PRMT6 (0.42) | — | |
| SCHEMBL7349981 | 0.73 | LMNA (0.32) | MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL4592572 | 0.72 | MTNR1A (0.39) | MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL4591521 | 0.72 | SLC6A3 (0.45) | — | |
| SCHEMBL23924861 | 0.71 | SLC6A3 (0.40) | — | |
| SCHEMBL10714899 | 0.71 | STS (0.45) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3655052 | 0.71 | SLC6A4 (0.41) | — | |
| SCHEMBL8481404 | 0.71 | OPRK1 (0.42) | — | |
| SCHEMBL30899722 | 0.71 | OPRK1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945212-A1 | TREATMENT OF DIABETES | NEUROSEARCH A/S (DK) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007051594-A1 | TREATMENT OF DIABETES | NEUROSEARCH A/S (DK) | 2007-05-10 | — | — | WO | disclosed |