Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979443 | 0.74 | HRH3 (0.38) | KDM4EALDH1A1 | |
| Bromide SCHEMBL6890863 | 0.73 | KDM4E (0.37) | KDM4EALDH1A1 | |
| SCHEMBL8947196 | 0.72 | KDM4E (0.45) | KDM4EALDH1A1LMNAPOLBPKM | |
| SCHEMBL7349988 | 0.72 | OPRL1 (0.32) | KDM4ESMN1; SMN2 | |
| SCHEMBL21683425 | 0.70 | OPRM1 (0.36) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL4591524 | 0.70 | SLC6A3 (0.42) | MEN1KMT2A | |
| SCHEMBL8946980 | 0.69 | HTR2C (0.43) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL19850549 | 0.69 | OPRL1 (0.37) | MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8843548 | 0.68 | SMN1; SMN2 (0.44) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL27338135 | 0.68 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945212-A1 | TREATMENT OF DIABETES | NEUROSEARCH A/S (DK) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007051594-A1 | TREATMENT OF DIABETES | NEUROSEARCH A/S (DK) | 2007-05-10 | — | — | WO | disclosed |