Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SORD | Q00796 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL459067 | 0.87 | FDPS (0.38) | FDPSGAASORDP2RX7ALDH1A1 | |
| Phosphoric Acid SCHEMBL938025 | 0.87 | FDPS (0.38) | FDPSGAASORDP2RX7ALDH1A1 | |
| SCHEMBL239378 | 0.79 | — | — | |
| SCHEMBL31429819 | 0.78 | FDPS (0.37) | FDPSBLMTDP1GAAP2RX7 | |
| SCHEMBL459237 | 0.75 | TSHR (0.40) | FDPSBTN3A1 | |
| Pyrophosphoric Acid SCHEMBL28298467 | 0.74 | HSP90AA1 (0.55) | FDPSBLMTDP1P2RX7INPPL1 | |
| SCHEMBL459068 | 0.72 | FDPS (0.39) | FDPSGAAP2RX7INPPL1CYP2C9 | |
| Pyridine SCHEMBL15552200 | 0.69 | NAPRT (0.45) | TDP1GAASORDALDH1A1L3MBTL1 | |
| SCHEMBL939997 | 0.69 | PGK1 (0.46) | FDPSP2RX7 | |
| Pyrophosphoric Acid SCHEMBL28436036 | 0.68 | FDPS (0.77) | FDPSBLMTDP1ALDH1A1INPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022411-A1 | MICROBIAL CELL FACTORIES PRODUCING THIAMINE | BIOSYNTIA APS (DK) | 2026-01-22 | — | — | US | disclosed |
| EP-4555076-A1 | MICROBIAL CELL FACTORIES PRODUCING THIAMINE | Biosyntia ApS (DK) | 2025-05-21 | — | — | EP | disclosed |
| CN-119731312-A | Microbial cell factory for producing thiamine | 拜奥信尼亚私营有限责任公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20240368659-A1 | MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS | BIOSYNTIA APS (DK) | 2024-11-07 | — | — | US | disclosed |
| EP-4370653-A2 | MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS | Biosyntia ApS (DK) | 2024-05-22 | — | — | EP | disclosed |
| CN-117897476-A | Microbial cell factory for producing vitamin B compounds | 拜奥信尼亚私营有限责任公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2024013212-A1 | MICROBIAL CELL FACTORIES PRODUCING THIAMINE | BIOSYNTIA APS (DK) | 2024-01-18 | — | — | WO | disclosed |
| WO-2023285585-A2 | MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS | BIOSYNTIA APS (DK) | 2023-01-19 | — | — | WO | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-9057063-B2 | Genetically modified biological cells | O'Keefe, Theresa (US) | 2015-06-16 | — | — | US | disclosed |
| US-20130198900-A1 | \"THIAMINE PYROPHOSPHATE (TPP) RIBOSWITCH MUTANTS PRODUCING VITAMIN B1 ENRICHED FOOD AND FEED CROPS\ | BEN-GURION UNIVERSITY OF THE NEGEV (IL) | 2013-08-01 | — | — | US | disclosed |
| EP-2614150-A1 | THIAMINE PYROPHOSPHATE (TPP) RIBOSWITCH MUTANTS PRODUCING VITAMIN B1 ENRICHED FOOD AND FEED CROPS | Yeda Research and Development Co. Ltd. (IL) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032522-A1 | THIAMINE PYROPHOSPHATE (TPP) RIBOSWITCH MUTANTS PRODUCING VITAMIN B1 ENRICHED FOOD AND FEED CROPS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2012-03-15 | — | — | WO | disclosed |
| US-7869957-B2 | Methods and systems to identify operational reaction pathways | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-01-11 | — | — | US | disclosed |
| US-20100304432-A1 | GENETICALLY MODIFIED BIOLOGICAL CELLS | O'KEEFE, THERESA | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022411-A1 | MICROBIAL CELL FACTORIES PRODUCING THIAMINE | AHCY, SHMT1, MTHFD1 | FDPS 5/4885BLM 4166/4885TDP1 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.