Cyclamic Acid

Cyclamic Acid

SCHEMBL4592737

O=S(=O)([O-])NC1CCCCC1.[K+]

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Cyclamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.91
CA7 P43166 3/20 0.91
CA14 Q9ULX7 3/20 0.91
CA9 Q16790 1/20 0.91
CA1 P00915 2/20 0.61
CA2 P00918 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
RECQL P46063 1/20 0.50
ALDH1A1 P00352 6/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclamic Acid SCHEMBL28963281 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL692781 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL2188654 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL9591547 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL414415 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL66221 0.95 CA12 (1.00) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL1532404 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL10856451 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL1457947 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL28154733 0.95 CA12 (1.00) CA12CA7CA14CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3510010-B1 TASTE MODULATING ALDEHYDE TAKASAGO PERFUMERY CO LTD (JP) 2023-09-06 EP claimed
US-11540542-B2 Taste modulating aldehydes TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-01-03 US claimed
EP-1919439-A2 PROCESS FOR BLEACHING KERATIN FIBERS The Procter and Gamble Company (US) 2008-05-14 EP claimed
EP-1919440-A2 AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER The Procter and Gamble Company (US) 2008-05-14 EP claimed
US-20070231283-A1 Process for bleaching keratin fibers PROCTER & GAMBLE COMPANY, THE 2007-10-04 US claimed
US-20070067925-A1 Agent for simultaneously lightening and coloring of fibers PROCTER & GAMBLE COMPANY, THE 2007-03-29 US claimed
WO-2007026327-A2 PROCESS FOR BLEACHING KERATIN FIBERS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO claimed
WO-2007026328-A2 AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO claimed
EP-1759685-A1 Agent for simultaneous lightening and coloring of keratin fibres containing a sulfamate bleach booster Wella Aktiengesellschaft (DE) 2007-03-07 EP claimed
EP-1759684-A1 Process for bleaching keratin fibers Wella Aktiengesellschaft (DE) 2007-03-07 EP claimed
EP-4642439-A1 A STABLE READY TO USE SUSPENSION OF STIRIPENTOL Kinedexe UK Limited (GB) 2025-11-05 EP disclosed
EP-4473977-A2 PHARMACEUTICAL COMPOSITION IN THE FORM OF A CHEWABLE TABLET OF DIOSMIN OR A FLAVONOID FRACTION COMPRISING SAME Les Laboratoires Servier (FR) 2024-12-11 EP disclosed
EP-3823588-B1 PHARMACEUTICAL COMPOSITION IN THE FORM OF A CHEWABLE TABLET OF DIOSMIN OR OF A FLAVONOID MOIETY COMPRISING DIOSMIN SERVIER LAB (FR) 2024-10-23 EP disclosed
WO-2024141890-A1 A STABLE READY TO USE SUSPENSION OF STIRIPENTOL. Kinedexe UK Limited (GB) 2024-07-04 WO disclosed
EP-4352110-A1 METHOD FOR MODIFYING STARCH BY HYDROTHERMAL TREATMENT, STARCH OBTAINED BY THIS METHOD AND USES THEREOF INNOVI (FR) 2024-04-17 EP disclosed
WO-2007026327-A2 PROCESS FOR BLEACHING KERATIN FIBERS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed
WO-2007026328-A2 AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed
EP-1759685-A1 Agent for simultaneous lightening and coloring of keratin fibres containing a sulfamate bleach booster Wella Aktiengesellschaft (DE) 2007-03-07 EP disclosed
EP-1759684-A1 Process for bleaching keratin fibers Wella Aktiengesellschaft (DE) 2007-03-07 EP disclosed
CN-1144627-A Sweetening agent and its production method MIAO CHENLIN (CN) 1997-03-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070067925-A1 Agent for simultaneously lightening and coloring of fibers KIT, KRT18, H1-5 CA12 130/4885CA7 80/4885CA14 186/4885
US-11540542-B2 Taste modulating aldehydes TAS2R10, TAS2R50, TAS2R1 CA12 1081/4885CA7 1892/4885CA14 912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.