Cyclamic Acid

Cyclamic Acid

SCHEMBL66221

O=S(=O)([O-])NC1CCCCC1.[Na+]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cyclamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 3/20 1.00
CA1 known ✓ P00915 2/20 0.61
CA2 known ✓ P00918 1/20 0.56
CA7 P43166 3/20 1.00
CA14 Q9ULX7 3/20 1.00
CA9 Q16790 1/20 1.00
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
RECQL P46063 1/20 0.50
ALDH1A1 P00352 6/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclamic Acid SCHEMBL28154733 1.00 CA12 (1.00) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL28188952 0.98 CA12 (0.95) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL30645235 0.98 CA12 (0.95) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL2188654 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL9591547 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL10856451 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL1457947 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL414415 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL4592737 0.95 CA12 (0.91) CA12CA7CA14CA9CA1
Cyclamic Acid SCHEMBL1532404 0.95 CA12 (0.91) CA12CA7CA14CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20036 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080093-A Compounds effective in treating liver toxicity and fatty liver disease and uses thereof 2026-05-26 CN claimed
CN-121086958-B Bacterial strain for removing sodium cyclamate through synergistic reinforcement, and mycoalgae symbiotic system and application 南昌大学 2026-05-22 CN claimed
CN-122056974-A Traditional Chinese medicine composition for preventing and treating bone marrow suppression and leucopenia caused by tumor chemoradiotherapy and preparation method and application thereof 河南医药大学第一附属医院(河南省结核病医院) 2026-05-19 CN claimed
US-12629377-B2 Lamotrigine oral liquid suspension and use thereof ROWP IP HOLDING II LLC 2026-05-19 US claimed
CN-119413976-B Detection method and kit for sodium cyclamate in white spirit 四川省食品检验研究院 2026-05-19 CN claimed
CN-122056801-A Buccal element and preparation method and application thereof 海狸医药科技(宁波)有限公司 2026-05-19 CN claimed
WO-2026099754-A1 METHOD FOR REDUCING VIRUS SHEDDING, TISSUE COLONIZATION, AND LYMPHOID DEPLETION CAUSED BY OR ASSOCIATED WITH PCV2 INFECTION BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2026-05-15 WO claimed
CN-122005485-A Metronidazole particles, preparation containing same and preparation method 上海惠永制药有限公司 2026-05-12 CN claimed
EP-4736863-A1 NOVEL MENTHOL-EUCALYPTUS OIL ANTITUSSIVE SPRAY AND USE THEREOF Sino-Shine Biopharmaceutical Co., Ltd (CN) 2026-05-06 EP claimed
WO-2026090022-A1 COMPOSITIONS AND METHODS FOR TASTE ENHANCEMENT OF BRAZZEIN GREENLAB, INC. (US) 2026-04-30 WO claimed
EP-0249398-A2 Oral compositions THE PROCTER & GAMBLE COMPANY (US) 1987-12-16 EP claimed
US-4680064-A Phosphate conversion coating accelerators GERHARD COLLARDIN GMBH (DE) 1987-07-14 US claimed
US-4574081-A QUATERNARY AMMONIUM COMPOUND, ANETHOLE, MENTHOL, PEPPERMINT, AND SWEETENING AGENTS COLGATE-PALMOLIVE CO. (US) 1986-03-04 US claimed
US-RE31954-E Oral composition COLGATE-PALMOLIVE COMPANY (US) 1985-07-23 US claimed
EP-0061654-B1 VINCAMINE CYCLAMATE, PROCESS FOR ITS PREPARATION AND MEDICAMENTS CONTAINING IT Heinrich Mack Nachf. (DE) 1985-07-10 EP claimed
US-4361580-A TASTELESS ANTIINFLAMMATORY AGENT THE UPJOHN MANUFACTURING COMPANY (US) 1982-11-30 US claimed
US-4357354-A SUGARS, SUGAR ALCOHOLS, AIR VOIDS NABISCO BRANDS, INC. (US) 1982-11-02 US claimed
US-4317837-A VISCOSITY CONTROLLED LIFE SAVERS, INC. (US) 1982-03-02 US claimed
US-4252830-A FILLERS, ARTIFICIAL SWEETENER LIFE SAVERS, INC. (US) 1981-02-24 US claimed
US-4241091-A HIGHER VOLUME LIFE SAVERS, INC. (US) 1980-12-23 US claimed