Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193246 | 0.86 | CHRNB2 (0.42) | TSHRTRPA1ALDH1A1 | |
| SCHEMBL8018943 | 0.75 | ALDH1A1 (0.42) | ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL7952407 | 0.75 | LMNA (0.46) | ALDH1A1HTTUSP2LMNAHPGD | |
| SCHEMBL11637235 | 0.75 | TSHR (0.48) | TSHRTRPA1DPP4F2ALDH1A1 | |
| SCHEMBL28555666 | 0.74 | DPP4 (0.38) | TSHRTRPA1DPP4F2 | |
| SCHEMBL7370019 | 0.74 | CYP2D6 (0.39) | TSHRTRPA1DPP4F2LMNA | |
| SCHEMBL7370022 | 0.74 | CYP2D6 (0.39) | TSHRTRPA1DPP4F2LMNA | |
| SCHEMBL819626 | 0.72 | ESR1 (0.56) | TSHRTRPA1DPP4F2ALDH1A1 | |
| SCHEMBL6309534 | 0.72 | ESR1 (0.56) | TSHRTRPA1DPP4F2ALDH1A1 | |
| SCHEMBL1325882 | 0.72 | TSHR (0.56) | TSHRTRPA1DPP4F2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118603958-A | Raman analysis method for ALS, APOC3, C3 and FCN2 proteins and biological application | 上海市第四人民医院 | 2024-09-06 | — | — | CN | claimed |
| EP-1799638-B1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA HOLDING INC (CH) | 2008-07-30 | — | — | EP | claimed |
| CN-118603958-A | Raman analysis method for ALS, APOC3, C3 and FCN2 proteins and biological application | 上海市第四人民医院 | 2024-09-06 | — | — | CN | disclosed |
| CN-110240554-B | Alpha-thioether aryl acetonitrile compound and synthetic method thereof | 上海大学 | 2021-02-23 | — | — | CN | disclosed |
| CN-102548769-A | Lithographic printing plate precursor | FUJIFILM CORP | 2012-07-04 | — | — | CN | disclosed |
| US-7405228-B2 | Antibacterial cyano-(substituted)-methylenepiperidinophenyl oxazolidinones targeting multiple ribonucleoprotein sites | WOCKHARDT LIMITED (IN) | 2008-07-29 | — | — | US | disclosed |
| EP-1565461-A2 | ANTIBACTERIAL SUBSTITUTED CYANOMETHYL(ENE)PIPERIDINOPHENYL OXAZOLIDINONES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Patel, Mahesh V. (IN) | 2005-08-24 | — | — | EP | disclosed |
| US-20040063954-A1 | Antibacterial cyano-(substituted)-methylenepiperidinophenyl oxazolidinones targeting multiple ribonucleoprotein sites | WOCKHARDT LIMITED | 2004-04-01 | — | — | US | disclosed |
| WO-2004007489-A2 | ANTIBACTERIAL SUBSTITUTED CYANOMETHYL (ENE) PIPERIDINOPHENYL OXAZOLIDINONES, PROCESS OR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WOCKHARDT LIMITED (IN) | 2004-01-22 | — | — | WO | disclosed |
| EP-0151072-B1 | DERIVATIVES OF METHYLENEDIPHOSPHONIC ACID, PROCESS FOR THEIR PREPARATION AND ANTIRHEUMATIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1988-03-09 | — | — | EP | disclosed |
| EP-0151072-A2 | Derivatives of methylenediphosphonic acid, process for their preparation and antirheumatic pharmaceutical compositions containing them | SANOFI (FR) | 1985-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063954-A1 | Antibacterial cyano-(substituted)-methylenepiperidinophenyl oxazolidinones targeting multiple ribonucleoprotein sites | POLRMT, RNASEL, RNASE1 | TSHR 4634/4885TRPA1 3933/4885DPP4 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.