SCHEMBL4193147

SCHEMBL4193147

CCCN(O)c1ccc(N)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.50
TSHR P16473 5/20 0.50
TDP1 Q9NUW8 4/20 0.50
ALDH1A1 P00352 4/20 0.50
MAPK1 P28482 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
PSMD14 O00487 1/20 0.50
RECQL P46063 1/20 0.50
GFER P55789 1/20 0.50
TP53 P04637 1/20 0.44
ALOX15 P16050 1/20 0.44
CYP1A2 P05177 4/20 0.41
MAPT P10636 3/20 0.41
CYP2D6 P10635 3/20 0.41
CYP2C19 P33261 3/20 0.41
CYP2C9 P11712 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP19A1 P11511 1/20 0.36
LMNA P02545 5/20 0.36
GAA P10253 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL459307 0.82 ALDH1A1 (0.60) CYP3A4TSHRTDP1ALDH1A1MAPK1
SCHEMBL17800265 0.80 ALDH1A1 (0.42) TSHRTDP1ALDH1A1TP53CYP2C19
SCHEMBL1389940 0.77 TP53 (0.47) CYP3A4TSHRALDH1A1TP53CYP2C19
SCHEMBL5685305 0.77 TDP1 (0.54) CYP3A4TSHRTDP1ALDH1A1MAPK1
SCHEMBL33801 0.77 TDP1 (0.67) CYP3A4TSHRTDP1ALDH1A1MAPK1
SCHEMBL1924408 0.76 TDP1 (0.52) CYP3A4TSHRTDP1ALDH1A1MAPK1
SCHEMBL12613338 0.75 MLYCD (0.33) L3MBTL1NPSR1
SCHEMBL4188894 0.75 IDO1 (0.34) ALDH1A1MAPK1MAPTKDM4EGAA
SCHEMBL9642517 0.75 HPGD (0.52) ALDH1A1TP53MAPTLMNA
SCHEMBL7520164 0.74 ALDH1A1 (0.75) CYP3A4TSHRTDP1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
EP-4739272-A1 OXIDATIVE HAIR COLOURING COMPOSITION Wella Germany GmbH (DE) 2026-05-13 EP claimed
EP-4731170-A1 OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE Wella Germany GmbH (DE) 2026-04-29 EP claimed
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents WELLA GERMANY GMBH (DE) 2026-03-03 US claimed
EP-4552630-A1 RESORCINOL FREE PERMANENT HAIR COLOR COMPOSITION AND METHOD Wella Operations US, LLC (US) 2025-05-14 EP claimed
WO-2025031867-A1 OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE WELLA GERMANY GMBH (DE) 2025-02-13 WO claimed
WO-2025008339-A1 OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2025-01-09 WO claimed
EP-4452203-A1 PROCESS FOR DYEING KERATIN FIBRES USING A COSMETIC COMPOSITION COMPRISING PROPANE-1,3-DIOL AND A DYEING COMPOSITION L'OREAL (FR) 2024-10-30 EP claimed
US-20240342067-A1 Hair Coloring Compositions Comprising 2-Amino-1-Propanol As Alkalising Agents WELLA GERMANY GMBH (DE) 2024-10-17 US claimed
WO-2022129377-A1 COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A PARTICULAR CARBOXYLIC ACID L'OREAL (FR) 2022-06-23 WO claimed
WO-2022129352-A1 COSMETIC COMPOSITION COMPRISING A COMBINATION OF TWO PARTICULAR COUPLERS AND N,N-DICARBOXYMETHYLGLUTAMIC ACID AND/OR ITS SALTS L'OREAL (FR) 2022-06-23 WO claimed
WO-2022129379-A1 COMPOSITION COMPRISING TWO PARTICULAR OXIDATION DYE PRECURSORS, AND A PARTICULAR CARBOXYLIC ACID L'OREAL (FR) 2022-06-23 WO claimed
WO-2022129372-A1 COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND AN ALKYL(POLY)GLYCOSIDE L'OREAL (FR) 2022-06-23 WO claimed
WO-2022129350-A1 COSMETIC COMPOSITION COMPRISING A COMBINATION OF TWO PARTICULAR COUPLERS AND AN OXYETHYLENATED FATTY ACID ESTER OF SORBITAN L'OREAL (FR) 2022-06-23 WO claimed
WO-2022129369-A1 COMPOSITION COMPRISING TWO PARTICULAR OXIDATION DYE PRECURSORS, AN OXYETHYLENATED FATTY ACID ESTER OF SORBITAN AND A FATTY ACID L'OREAL (FR) 2022-06-23 WO claimed
US-10639257-B2 Composition for colouring keratin fibres BEAUTY & BUSINESS S.P.A. (IT) 2020-05-05 US claimed
US-20190117541-A1 COMPOSITION FOR COLOURING KERATIN FIBRES BEAUTY & BUSINESS S.P.A. (IT) 2019-04-25 US claimed
US-9993413-B2 Keratin fibre dyeing composition BEAUTY & BUSINESS S.P.A. (IT) 2018-06-12 US claimed
US-20170258695-A1 KERATIN FIBRE DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-09-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents PHOSPHO1, ALDH7A1, AASDHPPT CYP3A4 2567/4885TSHR 2623/4885TDP1 1748/4885
US-12636241-B1 Method and composition for oxidative hair coloring POLB, DAO, ALPP CYP3A4 2719/4885TSHR 2634/4885TDP1 3594/4885
US-20240342067-A1 Hair Coloring Compositions Comprising 2-Amino-1-Propanol As Alkalising Agents ALDH7A1, PTMA, AAAS CYP3A4 1632/4885TSHR 2850/4885TDP1 311/4885
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) DEGS1, SGMS1, FABP4 CYP3A4 3722/4885TSHR 2881/4885TDP1 3998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.