Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616891 | 0.88 | GPR119 (0.31) | — | |
| SCHEMBL4593696 | 0.84 | GPR119 (0.34) | — | |
| SCHEMBL4469103 | 0.75 | HMOX1 (0.36) | — | |
| SCHEMBL4593293 | 0.74 | KDR (0.41) | — | |
| SCHEMBL4585478 | 0.74 | GPR119 (0.52) | — | |
| SCHEMBL28053867 | 0.74 | OPRK1 (0.41) | — | |
| SCHEMBL15789122 | 0.72 | — | — | |
| SCHEMBL8511076 | 0.72 | DGAT1 (0.45) | — | |
| SCHEMBL1853870 | 0.72 | FAAH (0.40) | — | |
| SCHEMBL20595693 | 0.70 | DPP4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558609-A4 | KINASE INHIBITORS | MERCK & CO INC (US) | 2008-05-28 | — | — | EP | disclosed |
| EP-1558609-A2 | KINASE INHIBITORS | Merck & Co., Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004041164-A2 | KINASE INHIBITORS | MERCK & CO., INC. (US) | 2004-05-21 | — | — | WO | disclosed |