Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592883 | 0.76 | RIPK1 (0.39) | ALDH1A1KMT2A | |
| SCHEMBL4593785 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL4593846 | 0.69 | HTR2A (0.33) | — | |
| SCHEMBL4654255 | 0.66 | DRD1 (0.48) | DRD1ALDH1A1KMT2ASLC22A12ALOX12 | |
| SCHEMBL4593434 | 0.66 | TSHR (0.35) | — | |
| SCHEMBL10910618 | 0.65 | DRD1 (0.39) | DRD1ULK1ALDH1A1KMT2ALRRK2 | |
| SCHEMBL4593190 | 0.63 | SLC6A3 (0.33) | — | |
| SCHEMBL8047355 | 0.62 | ALDH1A1 (0.50) | DRD1ALDH1A1KMT2ALRRK2ALOX12 | |
| SCHEMBL1434466 | 0.61 | SLC6A2 (0.43) | DRD1TNFALDH1A1KMT2AHTT | |
| SCHEMBL9356351 | 0.60 | SLC6A4 (0.40) | TNFKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937257-A1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2008-07-02 | — | — | EP | claimed |
| WO-2007037685-A1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2007-04-05 | — | — | WO | claimed |