Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841877 | 0.87 | ACHE (0.53) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27621135 | 0.82 | KMT2A (0.62) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5744305 | 0.82 | LMNA (0.55) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30087612 | 0.81 | PARP1 (0.48) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27438603 | 0.78 | PARP1 (0.46) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16162191 | 0.78 | LMNA (0.51) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6824958 | 0.78 | KIF11 (0.48) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16892960 | 0.76 | KCNN4 (0.72) | PARP1KIF11MAPTKMT2AKCNN4 | |
| SCHEMBL16892944 | 0.76 | PARP1 (0.52) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16892940 | 0.76 | CES2 (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693529-A | Synthesis method of 2-aza [2.2.2] octane compound | 河南师范大学 | 2023-09-05 | — | — | CN | disclosed |
| EP-1937257-A1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007037685-A1 | NOVEL ANTIBIOTICS COMPRISING BIS(1-ARYL-5-TETRAZ0LYL)METHANE DERIVATIVES | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2007-04-05 | — | — | WO | disclosed |