Adenosine Triphosphate

Adenosine Triphosphate

SCHEMBL4594623

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])OP(=O)([O-])OP(=O)(O)O)[C@@H](O)[C@H]1O.O.O.O.[Na+].[Na+]

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Adenosine Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 1/20 0.76
ADORA1 known ✓ P30542 1/20 0.76
PDE4D known ✓ Q08499 1/20 0.76
PDE3A known ✓ Q14432 1/20 0.76
P2RY1 P47900 9/20 0.76
P2RY2 P41231 3/20 0.76
P2RY11 Q96G91 3/20 0.76
SRC P12931 2/20 0.76
SMN1; SMN2 Q16637 2/20 0.76
TRPM2 O94759 2/20 0.76
DNPH1 O43598 1/20 0.76
PRKAB2 O43741 1/20 0.76
LDHA P00338 1/20 0.76
FBP1 P09467 1/20 0.76
PRKAG1 P54619 1/20 0.76
PRKAA2 P54646 1/20 0.76
KCNH2 Q12809 1/20 0.76
PRKAA1 Q13131 1/20 0.76
TAS1R3 Q7RTX0 1/20 0.76
TAS1R1 Q7RTX1 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Triphosphate SCHEMBL3498805 1.00 P2RY1 (0.76) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Triphosphate SCHEMBL29760430 1.00 P2RY1 (0.76) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Triphosphate SCHEMBL26184967 1.00 P2RY1 (0.76) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Triphosphate SCHEMBL29371640 1.00 P2RY1 (0.76) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Triphosphate SCHEMBL29352529 0.99 P2RY1 (0.78) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Triphosphate SCHEMBL28359 0.99 P2RY1 (0.78) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Triphosphate SCHEMBL27783353 0.98 P2RY1 (0.76) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Triphosphate SCHEMBL3332142 0.98 P2RY1 (0.76) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Triphosphate SCHEMBL27881873 0.98 P2RY1 (0.76) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Triphosphate SCHEMBL30786396 0.98 P2RY1 (0.76) P2RY1P2RY2P2RY11SRCSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539338-A Disodium adenosine triphosphate trihydrate crystal and preparation method thereof 苏州赜文医药科技有限公司 2022-05-27 CN claimed
US-20250268852-A1 MICROBIOTA IMPROVING AGENT SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2025-08-28 US disclosed
EP-4494696-A1 MICROBIOTA IMPROVING AGENT Sanyo Chemical Industries, Ltd. (JP) 2025-01-22 EP disclosed
WO-2024090537-A1 ZINC POLYPHOSPHATE AND METHOD FOR PRODUCING SAME カムイファーマ株式会社 2024-05-02 WO disclosed
WO-2023204274-A1 MICROBIOTA IMPROVING AGENT 三洋化成工業株式会社 2023-10-26 WO disclosed
CN-114539338-A Disodium adenosine triphosphate trihydrate crystal and preparation method thereof 苏州赜文医药科技有限公司 2022-05-27 CN disclosed
CN-114539338-A Disodium adenosine triphosphate trihydrate crystal and preparation method thereof 苏州赜文医药科技有限公司 2022-05-27 CN disclosed
CN-114539338-A Disodium adenosine triphosphate trihydrate crystal and preparation method thereof 苏州赜文医药科技有限公司 2022-05-27 CN disclosed
CN-111411102-B Preparation method of ZIF-8/enzyme composite material 复旦大学 2022-02-15 CN disclosed
EP-0973938-B1 THE USE OF NADPH AND NADH ANALOGS IN THE MEASUREMENT OF ENZYME ACTIVITIES AND METABOLITES SPECIALTY ASSAYS INC (US) 2008-01-02 EP disclosed
EP-0973938-A4 THE USE OF NADPH AND NADH ANALOGS IN THE MEASUREMENT OF ENZYME ACTIVITIES AND METABOLITES SPECIALTY ASSAYS INC (US) 2000-04-26 EP disclosed
EP-0973938-A1 THE USE OF NADPH AND NADH ANALOGS IN THE MEASUREMENT OF ENZYME ACTIVITIES AND METABOLITES Specialty Assays, Inc. (US) 2000-01-26 EP disclosed
US-5801006-A Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites SPECIALTY ASSAYS, INC. (US) 1998-09-01 US disclosed
WO-1998033936-A1 THE USE OF NADPH AND NADH ANALOGS IN THE MEASUREMENT OF ENZYME ACTIVITIES AND METABOLITES SPECIALTY ASSAYS, INC. (US) 1998-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250268852-A1 MICROBIOTA IMPROVING AGENT TLR1, TLR4, TYR ADRB2 2931/4885ADORA1 1314/4885PDE4D 3946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.