Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396164 | 0.98 | POLB (0.41) | POLBALDH1A1MAPTHTTNOS3 | |
| Iodide SCHEMBL5092606 | 0.95 | POLB (0.40) | POLBALDH1A1MAPTHTTNOS3 | |
| SCHEMBL29043862 | 0.95 | POLB (0.40) | POLBALDH1A1MAPTHTTNOS3 | |
| Bromide SCHEMBL16928609 | 0.95 | POLB (0.40) | POLBALDH1A1MAPTHTTNOS3 | |
| Hydrochloric Acid SCHEMBL233673 | 0.95 | POLB (0.40) | POLBALDH1A1MAPTHTTNOS3 | |
| Bromide SCHEMBL5088452 | 0.95 | POLB (0.40) | POLBALDH1A1MAPTHTTNOS3 | |
| Hydrochloric Acid SCHEMBL5510042 | 0.95 | POLB (0.40) | POLBALDH1A1MAPTHTTNOS3 | |
| Ethylene SCHEMBL28200619 | 0.93 | POLB (0.39) | POLBALDH1A1MAPTHTTNOS3 | |
| Bicarbonate SCHEMBL21957733 | 0.89 | ALDH1A1 (0.37) | POLBALDH1A1MAPTHTTGABRA1 | |
| Oxalic Acid SCHEMBL21957810 | 0.87 | ALDH1A1 (0.36) | POLBALDH1A1MAPTHTTGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119923173-B | N-type doping method of organic semiconductor and application thereof | 宁波天璇新材料科技有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-119923173-A | N-type doping method of organic semiconductor and application thereof | 宁波天璇新材料科技有限公司 | 2025-05-02 | — | — | CN | claimed |
| US-7727718-B2 | Reagents for storage and preparation of samples for DNA analysis | MOLECULAR RESEARCH CENTER, INC. (US) | 2010-06-01 | — | — | US | claimed |
| EP-1833983-A1 | REAGENTS AND METHODS FOR STORAGE AND PROCESSING OF BIOLOGICAL SAMPLES FOR DNA ANALYSIS | Molecular Research Center, Inc. (US) | 2007-09-19 | — | — | EP | claimed |
| WO-2006073497-A1 | REAGENTS AND METHODS FOR STORAGE AND PROCESSING OF BIOLOGICAL SAMPLES FOR DNA ANALYSIS | MOLECULAR RESEARCH CENTER, INC. (US) | 2006-07-13 | — | — | WO | claimed |
| US-20060147944-A1 | Reagents and methods for storage and processing of biological samples for DNA analysis | MOLECULAR RESEARCH CENTER, INC. | 2006-07-06 | — | — | US | claimed |
| CN-122037155-A | Hollow container and method for producing polycarbonate resin | 三菱化学株式会社 | 2026-05-15 | — | — | CN | disclosed |
| US-20260118767-A1 | REVERSE PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-04-30 | — | — | US | disclosed |
| EP-2371877-B1 | POLYCARBONATE RESIN, POLYCARBONATE RESIN COMPOSITION, OPTICAL FILM, AND POLYCARBONATE RESIN MOLDED ARTICLE | MITSUBISHI CHEM CORP (JP) | 2026-04-29 | — | — | EP | disclosed |
| US-12599937-B2 | Water-based, high-efficiency chemical reagent for substrate surface particle removal | APPLIED MATERIALS, INC. (US) | 2026-04-14 | — | — | US | disclosed |
| US-20260098129-A1 | THERMOPLASTIC RESIN AND MOLDED BODY CONTAINING THERMOPLASTIC RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-04-09 | — | — | US | disclosed |
| US-20260071030-A1 | THERMOPLASTIC RESIN, MOLDED BODY CONTAINING THERMOPLASTIC RESIN, AND OPTICAL LENS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-03-12 | — | — | US | disclosed |
| US-20260062520-A1 | THERMOPLASTIC RESIN AND MOLDED OBJECT INCLUDING THERMOPLASTIC RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-0427392-B1 | Improved method of casting a reactive metal against a surface formed from an improved slurry containing yttria | PCC AIRFOILS INC (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5324790-A | Esterification of carboxylate containing polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |
| WO-1994007925-A1 | ESTERIFICATION OF CARBOXYLATE CONTAINING POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-04-14 | — | — | WO | disclosed |
| US-5221336-A | Slurry comprising water, binder, yttria, source of hydroxyl ions to prevent gelation | PCC AIRFOILS, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0427392-A2 | Improved method of casting a reactive metal against a surface formed from an improved slurry containing yttria | PCC Airfoils, Inc. (US) | 1991-05-15 | — | — | EP | disclosed |
| US-4947927-A | CONTAINING HYDROXYL COMPOUND | PCC AIRFOILS, INC. (US) | 1990-08-14 | — | — | US | disclosed |
| US-4209643-A | Preparation of acetals | ETHYL CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062520-A1 | THERMOPLASTIC RESIN AND MOLDED OBJECT INCLUDING THERMOPLASTIC RESIN | RER1, PUF60, SEM1 | POLB 2272/4885ALDH1A1 116/4885MAPT 1844/4885 |
| US-20260071030-A1 | THERMOPLASTIC RESIN, MOLDED BODY CONTAINING THERMOPLASTIC RESIN, AND OPTICAL LENS | DERL1, WDR1, RIF1 | POLB 4187/4885ALDH1A1 521/4885MAPT 1049/4885 |
| US-20260118767-A1 | REVERSE PATTERNING PROCESS | EFNA1, EPHA4, ETV6 | POLB 850/4885ALDH1A1 4452/4885MAPT 2567/4885 |
| US-20260098129-A1 | THERMOPLASTIC RESIN AND MOLDED BODY CONTAINING THERMOPLASTIC RESIN | RER1, EIF2AK1, RIOK1 | POLB 3500/4885ALDH1A1 46/4885MAPT 3531/4885 |
| US-12599937-B2 | Water-based, high-efficiency chemical reagent for substrate surface particle removal | STUB1, CD2, EPCAM | POLB 1626/4885ALDH1A1 528/4885MAPT 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.