SCHEMBL4596050

SCHEMBL4596050

C=C(CCCNC(=O)CC(C)=O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ADRA1A P35348 2/20 0.37
CASP2 P42575 1/20 0.36
TSHR P16473 1/20 0.35
KDM4E B2RXH2 2/20 0.34
MAPK1 P28482 1/20 0.34
HIF1A Q16665 1/20 0.34
NAAA Q02083 1/20 0.34
ATM Q13315 1/20 0.34
ECE1 P42892 1/20 0.33
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33
SLC6A5 Q9Y345 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FAAH O00519 1/20 0.33
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4596397 0.89 ECE1 (0.39) MEN1KMT2AADRA1ACASP2KDM4E
SCHEMBL378843 0.82 KDM4E (0.54) ADRA1ATSHRKDM4EMAPK1HIF1A
SCHEMBL9317792 0.81 ALDH1A1 (0.56) MEN1KMT2ACASP2TSHRKDM4E
SCHEMBL2553506 0.80 ADRA1A (0.55) MEN1KMT2AADRA1ATSHRKDM4E
SCHEMBL1880850 0.79 PLA2G4A (0.39) ADRA1AKDM4EMAPK1HIF1AALDH1A1
SCHEMBL1011841 0.78 ALOX15 (0.35) ADRA1AKDM4EMAPK1HIF1AATM
SCHEMBL8995190 0.78 TSHR (0.49) MEN1KMT2AADRA1ATSHRKDM4E
SCHEMBL9841123 0.77 ADRA1A (0.62) MEN1KMT2AADRA1ATSHRKDM4E
SCHEMBL1091793 0.76 CASP2 (0.52) MEN1KMT2ACASP2TSHRKDM4E
SCHEMBL8544799 0.76 KEAP1 (0.42) ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1877864-B1 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF MERCK PATENT GMBH (DE) 2018-09-19 EP disclosed
WO-2013064890-A2 NANOCOMPOSITE NEGATIVE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-05-10 WO disclosed
US-20130105440-A1 NANOCOMPOSITE NEGATIVE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-05-02 US disclosed
EP-1877864-A2 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ Electronic Materials USA Corp. (US) 2008-01-16 EP disclosed
US-7247419-B2 Nanocomposite photosensitive composition and use thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2007-07-24 US disclosed
US-20070141510-A1 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF CHEN CHUNWEI 2007-06-21 US disclosed
WO-2006109121-A2 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ ELECTRONIC MATERIALS USA CORP. (DE) 2006-10-19 WO disclosed
US-20060228645-A1 Nanocomposite photosensitive composition and use thereof MERCK PATENT GMBH (DE) 2006-10-12 US disclosed
US-7078157-B2 Photosensitive composition and use thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2006-07-18 US disclosed
EP-1602010-A2 PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ Electronic Materials USA Corp. (US) 2005-12-07 EP disclosed
WO-2004077153-A2 PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2004-09-10 WO disclosed
US-20040175653-A1 Photosensitive composition and use thereof AZ ELECTRONIC MATERIALS USA CORP. 2004-09-09 US disclosed
US-6475697-B2 MULTILAYER; SUPPORT, SILVER HALIDE EMULSION, REDUCING AGENT, SUBBING AGENT AND BINDER KONICA CORPORATION (JP) 2002-11-05 US disclosed
US-20010038981-A1 Photothermographic dry imaging material easy to separate emulsion layer from support and method for separation KONICA CORPORATION (JP) 2001-11-08 US disclosed
US-6280917-B1 POLYMER HAVING AN ETHYLENICALLY UNSATURATED MONOMER UNIT CONTAINING AN ACTIVE METHYLENE GROUP AND AN ETHYLENICALLY UNSATURATED MONOMER UNIT SELECTED FROM METHACRYLIC ACID ESTER, ACRYLIC ACID ESTER, MALEIC ACID ESTER AND DIENE DERIVATIVE KONICA CORPORATION (JP) 2001-08-28 US disclosed
US-6239207-B1 Active-methylene functionalized latex polymer prepared in the presence of a hydrophilic isoprene sulfuric acid polymer, and sheet material comprising same KONICA CORPORATION (JP) 2001-05-29 US disclosed