Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | GABRE | P78334 | 2/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805515 | 0.73 | AKR1B1 (0.48) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL18805516 | 0.73 | AKR1B1 (0.48) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL8914656 | 0.72 | GABRA5 (0.44) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL18473272 | 0.70 | ADORA3 (0.52) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL583915 | 0.70 | AKR1B1 (0.60) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL4595837 | 0.67 | GABRP (0.67) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL25309255 | 0.66 | THRB (0.47) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL17670461 | 0.66 | TSHR (0.48) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL15157078 | 0.66 | HTT (0.45) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL27830212 | 0.65 | RXRA (0.41) | GABRA5GABRB2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161685-B1 | METHOD FOR REDUCING FLUORESCENCE QUENCHING IN BIOASSAYS | CIS BIO INT (FR) | 2008-01-09 | — | — | EP | disclosed |
| US-7309567-B1 | Method for reducing fluorescence quenching in bioassays | CIS BIO INTERNATIONAL (FR) | 2007-12-18 | — | — | US | disclosed |
| EP-1161685-A1 | METHOD FOR REDUCING FLUORESCENCE QUENCHING IN BIOASSAYS | CIS BIO INTERNATIONAL (FR) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055630-A1 | METHOD FOR REDUCING FLUORESCENCE QUENCHING IN BIOASSAYS | CIS BIO INTERNATIONAL (FR) | 2000-09-21 | — | — | WO | disclosed |