Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757446 | 0.84 | ABCG2 (0.44) | ABCG2TXNRD1TXNRD3TXNRD2NQO2 | |
| SCHEMBL13756967 | 0.81 | ITGB2 (0.40) | ALDH1A1HSD17B10 | |
| SCHEMBL13950616 | 0.76 | SRD5A2 (0.41) | TXNRD1TXNRD3TXNRD2NQO2CYP19A1 | |
| SCHEMBL13950622 | 0.76 | TXNRD1 (0.38) | ABCG2TXNRD1TXNRD3TXNRD2NQO2 | |
| SCHEMBL13950623 | 0.76 | AOC3 (0.36) | ABCG2TXNRD1TXNRD3TXNRD2NQO2 | |
| SCHEMBL13950626 | 0.76 | TXNRD1 (0.34) | ABCG2TXNRD1TXNRD3TXNRD2NQO2 | |
| SCHEMBL12446382 | 0.74 | NQO2 (0.46) | ABCG2TXNRD1TXNRD3TXNRD2NQO2 | |
| SCHEMBL12023132 | 0.74 | AOC3 (0.53) | ABCG2TXNRD1TXNRD3TXNRD2AOC3 | |
| SCHEMBL23635064 | 0.70 | TXNRD1 (0.40) | ABCG2TXNRD1TXNRD3TXNRD2NQO2 | |
| SCHEMBL14302834 | 0.70 | TXNRD1 (0.40) | ABCG2TXNRD1TXNRD3TXNRD2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673376-B2 | Laminate | DAIKIN INDUSTRIES. LTD. (JP) | 2023-06-13 | — | — | US | disclosed |
| US-9938204-B2 | Intermolecular C-H silylation of unactivated arenes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-06-22 | — | — | US | disclosed |
| US-20160200639-A1 | INTERMOLECULAR C-H SILYLATION OF UNACTIVATED ARENES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-07-14 | — | — | US | disclosed |
| US-9187498-B2 | Compound and asymmetric synthesis reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20150183807-A1 | Compound and Asymmetric Synthesis Reaction | MICROBIAL CHEM RES FOUND (JP) | 2015-07-02 | — | — | US | disclosed |
| US-9012649-B2 | Method for producing optically active 2-arylpiperidinium salt | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-04-21 | — | — | US | disclosed |
| US-8981123-B2 | Compound and asymmetric synthesis reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-03-17 | — | — | US | disclosed |
| EP-2563799-B1 | RUTHENIUM COMPLEX AND METHOD FOR PREPARING OPTICALLY ACTIVE ALCOHOL COMPOUND | TAKASAGO PERFUMERY CO LTD (JP) | 2015-02-11 | — | — | EP | disclosed |
| US-20140296539-A1 | Compound and Asymmetric Synthesis Reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2014-10-02 | — | — | US | disclosed |
| WO-2014139854-A1 | SELECTIVE HYDROGENATION OF ALDEHYDES WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2014-09-18 | — | — | WO | disclosed |
| US-20140213792-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERIDINIUM SALT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-07-31 | — | — | US | disclosed |
| WO-2014038666-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINE | 高砂香料工業株式会社 (JP) | 2014-03-13 | — | — | WO | disclosed |
| EP-2264000-A1 | RUTHENIUM COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINOALCOHOL COMPOUND | Nippon Soda Co., Ltd. (JP) | 2010-12-22 | — | — | EP | disclosed |
| US-7576118-B2 | Asymmetric hydrogenation process | MERCK & CO., INC. (US) | 2009-08-18 | — | — | US | disclosed |
| EP-1419815-B1 | Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes | TAKASAGO PERFUMERY CO LTD (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-7078568-B2 | Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-07-18 | — | — | US | disclosed |
| US-20050288531-A1 | Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes | SHIMIZU HIDEO | 2005-12-29 | — | — | US | disclosed |
| EP-1419815-A1 | Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes | Takasago International Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200639-A1 | INTERMOLECULAR C-H SILYLATION OF UNACTIVATED ARENES | CCNH, CTTN, CCRL2 | ABCG2 2048/4885TXNRD1 4592/4885TXNRD3 4085/4885 |
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | POF1B, FGFR1, COASY | ABCG2 1252/4885TXNRD1 4250/4885TXNRD3 4695/4885 |
| US-20150183807-A1 | Compound and Asymmetric Synthesis Reaction | CYP2E1, REV1, CYP19A1 | ABCG2 1319/4885TXNRD1 2499/4885TXNRD3 2542/4885 |
| US-20140296539-A1 | Compound and Asymmetric Synthesis Reaction | CYP2E1, REV1, CYP19A1 | ABCG2 1319/4885TXNRD1 2499/4885TXNRD3 2542/4885 |
| US-20050288531-A1 | Phosphine compounds, transition metal complexes with the compounds contained as ligands therein, and asymmetric synthesis catalysts containing the complexes | PHOSPHO1, PRMT1, PRMT9 | ABCG2 2141/4885TXNRD1 1503/4885TXNRD3 1784/4885 |
| US-20140213792-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERIDINIUM SALT | REN, KCNH3, KCNH2 | ABCG2 2962/4885TXNRD1 2252/4885TXNRD3 1457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.