SCHEMBL4597351

SCHEMBL4597351

c1ccc(-c2nc(-c3ccccc3)n(-n3c(-c4ccccc4)nc(-c4ccccc4)c3-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.43
KMT2A Q03164 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 2/20 0.43
USP2 O75604 1/20 0.43
HPGD P15428 1/20 0.43
MAPK1 P28482 1/20 0.43
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
CASP1 P29466 1/20 0.41
PDE10A Q9Y233 1/20 0.41
PKM P14618 1/20 0.41
LMNA P02545 2/20 0.39
HTT P42858 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11508710 0.85 PTGS2 (0.56) TDP1SMN1; SMN2GAA
SCHEMBL6362990 0.85 NPSR1 (0.61) TDP1L3MBTL1SMN1; SMN2HPGDMAPK1
SCHEMBL4869355 0.84 ADORA2A (0.46) TDP1KMT2ASMN1; SMN2MEN1KDM4E
SCHEMBL10033037 0.82 GAA (0.51) BCHEL3MBTL1SMN1; SMN2HPGDKDM4E
SCHEMBL20152219 0.82 HPGD (0.40) BCHEACHEL3MBTL1KMT2ASMN1; SMN2
SCHEMBL273205 0.81 TNK2 (0.39) BCHEACHEL3MBTL1KMT2ASMN1; SMN2
SCHEMBL29732755 0.80 HSD11B1 (0.49) BCHEACHETDP1SMN1; SMN2HPGD
SCHEMBL63728 0.80 HSD11B1 (0.49) BCHEACHETDP1SMN1; SMN2HPGD
SCHEMBL6362343 0.80 ADORA2A (0.42) BCHEACHEL3MBTL1KMT2ASMN1; SMN2
SCHEMBL822678 0.79 PTGER1 (0.56) TDP1HPGDKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100221663-A1 LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL, AND IMAGE FORMATION METHOD EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2010-09-02 US disclosed
EP-1397392-B1 ADHESIVE DETACKIFICATION METHOD 3M INNOVATIVE PROPERTIES CO (US) 2008-01-16 EP disclosed
US-20070284039-A1 ADHESIVE DETACKIFICATION 3M INNOVATIVE PROPERTIES COMPANY 2007-12-13 US disclosed
US-7258917-B2 Adhesive detackification 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-08-21 US disclosed
US-20050054785-A1 Adhesive detackification 3M INNOVATIVE PROPERTIES COMPANY 2005-03-10 US disclosed
US-6627309-B2 Mixture of addition polymer, activated by solvent, friction; containg photostabilizer 3M INNOVATIVE PROPERTIES COMPANY 2003-09-30 US disclosed
US-20030054138-A1 Adhesive detackification 3M INNOVATIVE PROPERTIES COMPANY 2003-03-20 US disclosed
US-5399458-A Process for making images employing a toner which has a tackiness that can be increased by actinic radiation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-21 US disclosed
US-4175964-A SUCCESSIVE SURFACE TREATMENT WITH AQUEOUS SOLUTIONS OF PHOSPHORIC ACID AND SILICIC ACID OR ITS SALTS FUJI PHOTO FILM CO., LTD. (JP) 1979-11-27 US disclosed