SCHEMBL273205

SCHEMBL273205

c1ccc(-c2nc(-c3ccccc3)n(-n3ccnc3-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
ESR1 P03372 1/20 0.37
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
KDR P35968 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ALDH1A1 P00352 1/20 0.36
NSD3 Q9BZ95 1/20 0.36
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4597351 0.81 BCHE (0.45) SMN1; SMN2BCHEACHEL3MBTL1ALDH1A1
SCHEMBL5192672 0.77 ESR1 (0.49) TNK2SMN1; SMN2ESR1KDRALDH1A1
SCHEMBL5201695 0.70 LMNA (0.50) TNK2SMN1; SMN2L3MBTL1ALDH1A1MAPK1
SCHEMBL6362990 0.69 NPSR1 (0.61) TNK2SMN1; SMN2L3MBTL1ALDH1A1HPGD
SCHEMBL11508710 0.69 PTGS2 (0.56) SMN1; SMN2
SCHEMBL4869355 0.68 ADORA2A (0.46) SMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL21359724 0.68 KDR (0.41) TNK2SMN1; SMN2ESR1KDRHPGD
SCHEMBL822678 0.67 PTGER1 (0.56) ALDH1A1HPGD
SCHEMBL4622519 0.67 HSD11B1 (0.41) SMN1; SMN2BCHEACHEALDH1A1NSD3
SCHEMBL20062953 0.67 ESR1 (0.41) ESR1KDRALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133651-B2 Lithographic printing plate comprising alkaline soluble and alkaline insoluble polymeric binders TENG GARY GANGHUI (US) 2012-03-13 US disclosed
US-8092984-B2 Lithographic printing plate having specific polymeric binders TENG GARY GANGHUI (US) 2012-01-10 US disclosed
US-7752966-B2 Method of developing laser sensitive lithographic printing plate TENG GARY GANGHUI 2010-07-13 US disclosed
US-7674571-B2 Laser sensitive lithographic printing plate comprising specific acrylate monomer and initiator TENG GARY GANGHUI 2010-03-09 US disclosed
US-20100055614-A1 Lithographic printing plate having specific polymeric binders TENG GARY GANGHUI 2010-03-04 US disclosed
US-20090130596-A1 Lithographic printing plate comprising alkaline soluble and alkaline insoluble polymeric binders TENG GARY GANGHUI 2009-05-21 US disclosed
US-20080271627-A1 Lithographic printing press and method for on-press imaging laser sensitive lithographic plate TENG GARY GANGHUI 2008-11-06 US disclosed
US-7427465-B2 On-press development of high speed laser sensitive lithographic printing plates TENG GARY GANGHUI 2008-09-23 US disclosed
US-20070196771-A1 Method of developing laser sensitive lithographic printing plate TENG GARY G 2007-08-23 US disclosed
US-20070172766-A1 Laser sensitive lithographic printing plate comprising specific acrylate monomer and initiator TENG GARY GANGHUI 2007-07-26 US disclosed
US-20060183049-A1 On-press development of high speed laser sensitive lithographic printing plates TENG GARY G 2006-08-17 US disclosed