Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17017116 | 0.97 | KCNH2 (0.34) | KCNH2CA12CA1CA9PYCR1 | |
| SCHEMBL13259384 | 0.95 | KCNH2 (0.35) | KCNH2CA12CA1CA9PYCR1 | |
| SCHEMBL8519897 | 0.90 | DNM1 (0.44) | KCNH2 | |
| SCHEMBL30156804 | 0.90 | DNM1 (0.44) | KCNH2 | |
| SCHEMBL30692301 | 0.90 | DNM1 (0.44) | KCNH2 | |
| SCHEMBL24693238 | 0.87 | EPHX1 (0.33) | KCNH2 | |
| SCHEMBL935039 | 0.86 | PYCR1 (0.38) | CA12CA9PYCR1 | |
| SCHEMBL16965227 | 0.85 | DNM1 (0.44) | KCNH2 | |
| SCHEMBL16587970 | 0.83 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL16922402 | 0.81 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595977-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | SANOFI (FR) | 2013-05-29 | — | — | EP | claimed |
| EP-2552900-A1 | PROCESS FOR PREPARING AMINOBENZOFURAN DERIVATIVES | SANOFI (FR) | 2013-02-06 | — | — | EP | claimed |
| EP-2542544-A1 | KETOBENZOFURAN DERIVATIVES, METHOD FOR SYNTHESISING SAME, AND INTERMEDIATES | SANOFI (FR) | 2013-01-09 | — | — | EP | claimed |
| WO-2012010802-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | SANOFI (FR) | 2012-01-26 | — | — | WO | claimed |
| WO-2011121245-A1 | PROCESS FOR PREPARING AMINOBENZOFURAN DERIVATIVES | SANOFI-AVENTIS (FR) | 2011-10-06 | — | — | WO | claimed |
| WO-2011107705-A1 | KETOBENZOFURAN DERIVATIVES, METHOD FOR SYNTHESISING SAME, AND INTERMEDIATES | SANOFI-AVENTIS (FR) | 2011-09-09 | — | — | WO | claimed |
| EP-1647555-B1 | THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME | INST RADIATION MED AMMS PLA (CN) | 2011-04-20 | — | — | EP | claimed |
| EP-1490326-B1 | METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS | BASF SE (DE) | 2010-12-29 | — | — | EP | claimed |
| US-7109377-B2 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-09-19 | — | — | US | claimed |
| EP-0857770-B1 | Coating compositions, hydrophilic films, and hydrophilic film-coated articles | SHINETSU CHEMICAL CO (JP) | 2004-09-22 | — | — | EP | claimed |
| US-20030082830-A1 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-01 | — | — | US | claimed |
| US-6448443-B1 | GENERATED FROM DIVERSIFIABLE SCAFFOLDS SYNTHESIZED FROM THE PYRIDINE-BASED TEMPLATE ISONICOTINAMIDE; ALSO PROVIDES A NOVEL ORTHO-NITROBENZYL PHOTOLINKER; SYNTHESIZED FROM A SHIKIMIC ACID BASED EPOXYOL TEMPLATE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-09-10 | — | — | US | claimed |
| WO-2000006525-A9 | SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS | HARVARD COLLEGE (US) | 2000-04-20 | — | — | WO | claimed |
| WO-2000006525-A2 | SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-02-10 | — | — | WO | claimed |
| EP-0630960-B1 | Lubricating oil composition | IDEMITSU KOSAN CO (JP) | 1999-08-25 | — | — | EP | claimed |
| EP-0507317-B1 | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-01-15 | — | — | EP | claimed |
| US-20240208898-A1 | ENAMINE N-OXIDES: SYNTHESIS AND APPLICATION TO HYPOXIA-RESPONSIVE PRODRUGS AND IMAGING AGENTS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| EP-4313013-A2 | ENAMINE N-OXIDES: SYNTHESIS AND APPLICATION TO HYPOXIA-RESPONSIVE PRODRUGS AND IMAGING AGENTS | Dana-Farber Cancer Institute, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| EP-0471609-B1 | Benzofuran Derivatives, Benzothiophenes, Indoles or Indolizines, Process for Production and Compositions containing them | SANOFI SA (FR) | 1996-11-27 | — | — | EP | disclosed |
| EP-0471609-A1 | Benzofuran Derivatives, Benzothiophenes, Indoles or Indolizines, Process for Production and Compositions containing them | SANOFI (FR) | 1992-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208898-A1 | ENAMINE N-OXIDES: SYNTHESIS AND APPLICATION TO HYPOXIA-RESPONSIVE PRODRUGS AND IMAGING AGENTS | ENO1, HIF1A, HIF1AN | KCNH2 2838/4885CA12 326/4885CA1 459/4885 |
| US-20030082830-A1 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | TKFC, NISCH, PTGIS | KCNH2 1011/4885CA12 3930/4885CA1 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.