Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 6/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597242 | 0.84 | JAK3 (0.42) | MC4ROPRM1ALDH1A1LMNA | |
| SCHEMBL17825622 | 0.82 | KMT2A (0.41) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4600708 | 0.76 | CYP2C19 (0.43) | ALDH1A1LMNAMEN1KMT2AGAA | |
| SCHEMBL4600313 | 0.75 | KCNA5 (0.41) | LMNAMEN1KMT2A | |
| SCHEMBL4598809 | 0.74 | CTSK (0.40) | LMNAMEN1KMT2A | |
| SCHEMBL4600484 | 0.74 | CTSK (0.40) | LMNAMEN1KMT2A | |
| SCHEMBL6466556 | 0.72 | MTNR1A (0.44) | CNR2MEN1KMT2A | |
| SCHEMBL26907022 | 0.71 | PRMT3 (0.48) | MC4ROPRM1LMNACNR2CES2 | |
| SCHEMBL6342824 | 0.71 | KCNA3 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27881358 | 0.71 | CES2 (0.37) | MC4RALDH1A1LMNACNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912946-A1 | PYRIDINE DERIVATIVES AS DIPEPTEDYL PEPTIDASE INHIBITORS | Eli Lilly and Company (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007015767-A1 | PYRIDINE DERIVATIVES AS DIPEPTEDYL PEPTIDASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |