Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 9/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL20337331 | 0.85 | TSHR (0.48) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL31467313 | 0.84 | — | — | |
| Glycinebetaine SCHEMBL8678519 | 0.84 | TSHR (0.53) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL4900209 | 0.84 | — | — | |
| Glycinebetaine SCHEMBL7739 | 0.84 | — | — | |
| Glycinebetaine SCHEMBL2803780 | 0.84 | TSHR (0.53) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL9785894 | 0.82 | TSHR (0.46) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL18957544 | 0.82 | FFAR3 (0.46) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL8725957 | 0.82 | — | — | |
| Glycinebetaine SCHEMBL4457941 | 0.82 | TSHR (0.50) | BBOX1TSHRALDH1A1LMNAAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345970-B1 | USE OF AMPHOTERIC POLYSACCHARIDE FOR TREATING TEXTILE FIBRE ARTICLES | RHODIA CHIMIE SA (FR) | 2008-04-16 | — | — | EP | claimed |
| US-7074919-B2 | Use of amphoteric polysaccharide for treating textile fiber articles | Chimie, Rhodia (FR) | 2006-07-11 | — | — | US | claimed |
| US-20040067864-A1 | Use of amphoteric polysaccharide for treating textile fibre articles | RHODIA CHIMIE (FR) | 2004-04-08 | — | — | US | claimed |
| US-20080306253-A1 | MATRIX MADE OF A POLYSACCHARIDE MODIFIED UNDER AN ELECTRON BEAM WITH A FUNCTIONAL ORGANOSILICON COMPOUND | RHODIA CHIMIE (FR) | 2008-12-11 | — | — | US | disclosed |
| EP-1345970-B1 | USE OF AMPHOTERIC POLYSACCHARIDE FOR TREATING TEXTILE FIBRE ARTICLES | RHODIA CHIMIE SA (FR) | 2008-04-16 | — | — | EP | disclosed |
| US-20070128142-A1 | Emulsion for conveying a hydrophobic active material to a substrate in aqueous medium | RHODIA CHIMIE (FR) | 2007-06-07 | — | — | US | disclosed |
| US-7074919-B2 | Use of amphoteric polysaccharide for treating textile fiber articles | Chimie, Rhodia (FR) | 2006-07-11 | — | — | US | disclosed |
| US-20060107469-A1 | Formulations designed to be applied on keratinous material and to be rinsed | RHODIA CHIMIE (FR) | 2006-05-25 | — | — | US | disclosed |
| US-20050281882-A1 | Matrix made of a polysaccharide modified under an electron beam with a functional organosilicon compound | RHODIA CHIMIE (FR) | 2005-12-22 | — | — | US | disclosed |
| EP-1553917-A1 | FORMULATIONS DESIGNED TO BE APPLIED ON KERATINOUS MATERIAL AND TO BE RINSED | Rhodia Chimie (FR) | 2005-07-20 | — | — | EP | disclosed |
| EP-1537271-A2 | TEXTILE RINSING FORMULATION | RHODIA CHIMIE (FR) | 2005-06-08 | — | — | EP | disclosed |
| US-20050097678-A1 | Polymer-based formulation for textile rinsing | RHODIA CHIMIE (FR) | 2005-05-12 | — | — | US | disclosed |
| US-20050028293-A1 | Rinsing formulation for textiles | RHODIA CHIMIE (FR) | 2005-02-10 | — | — | US | disclosed |
| US-20040067864-A1 | Use of amphoteric polysaccharide for treating textile fibre articles | RHODIA CHIMIE (FR) | 2004-04-08 | — | — | US | disclosed |
| WO-2004022839-A2 | TEXTILE RINSING FORMULATION | RHODIA CHIMIE (FR) | 2004-03-18 | — | — | WO | disclosed |
| WO-2004022680-A2 | POLYMER-BASED TEXTILE RINSING FORMULATION | RHODIA CHIMIE (FR) | 2004-03-18 | — | — | WO | disclosed |
| WO-2004022014-A1 | FORMULATIONS DESIGNED TO BE APPLIED ON KERATINOUS MATERIAL AND TO BE RINSED | RHODIA CHIMIE (FR) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060107469-A1 | Formulations designed to be applied on keratinous material and to be rinsed | KRT18, DSG1, CUTA | BBOX1 4124/4885TSHR 4620/4885ALDH1A1 2379/4885 |
| US-20050281882-A1 | Matrix made of a polysaccharide modified under an electron beam with a functional organosilicon compound | GYS2, MGAM, GYS1 | BBOX1 1611/4885TSHR 4750/4885ALDH1A1 4359/4885 |
| US-20070128142-A1 | Emulsion for conveying a hydrophobic active material to a substrate in aqueous medium | PHOSPHO1, PMM2, SAMM50 | BBOX1 2903/4885TSHR 4681/4885ALDH1A1 4337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.