Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600628 | 0.85 | EGFR (0.47) | MAPTALDH1A1EGFRKMT2AMEN1 | |
| SCHEMBL4600843 | 0.82 | RAB9A (0.50) | MAPTALDH1A1EGFRKMT2AMEN1 | |
| SCHEMBL25180670 | 0.78 | ALDH1A1 (0.57) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4601601 | 0.76 | EGFR (0.47) | MAPTALDH1A1EGFRKMT2ASMN1; SMN2 | |
| SCHEMBL4600130 | 0.75 | EGFR (0.47) | ALDH1A1EGFRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4602183 | 0.74 | EGFR (0.47) | MAPTEGFRKMT2AMEN1GAA | |
| SCHEMBL4601033 | 0.73 | EGFR (0.44) | EGFR | |
| SCHEMBL4602169 | 0.73 | EGFR (0.41) | ALDH1A1EGFRKMT2ASMN1; SMN2HPGD | |
| SCHEMBL27716400 | 0.73 | MAPT (0.42) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL226894 | 0.72 | GAA (0.57) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |