Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | FABP1 | P07148 | 1/20 | 0.43 |
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654460 | 0.97 | CALM1 (0.52) | CALM1TAAR1HSD17B10L3MBTL1MEN1 | |
| Ammonia Solution, Strong SCHEMBL27509627 | 0.97 | CALM1 (0.52) | CALM1TAAR1HSD17B10L3MBTL1MEN1 | |
| Methoxyamine SCHEMBL27403250 | 0.87 | TAAR1 (0.44) | CALM1TAAR1HSD17B10L3MBTL1MEN1 | |
| SCHEMBL30285062 | 0.81 | HRH3 (0.54) | HRH3 | |
| SCHEMBL2163588 | 0.80 | CALM1 (0.50) | CALM1TAAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL95081 | 0.80 | CALM1 (0.44) | CALM1TAAR1HSD17B10L3MBTL1MEN1 | |
| SCHEMBL2697397 | 0.78 | CALM1 (0.48) | CALM1TAAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL11307416 | 0.78 | L3MBTL1 (0.60) | HSD17B10L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL2634509 | 0.78 | PARP1 (0.44) | TAAR1MEN1KMT2ACYP1A2NPC1 | |
| SCHEMBL20659171 | 0.78 | L3MBTL1 (0.37) | CALM1TAAR1HSD17B10L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930525-A | Anti-amide herbicide benzyl pyrimidine compound suitable for seed coating and application thereof | 江苏里下河地区农业科学研究所 | 2025-05-06 | — | — | CN | claimed |
| CN-118666758-A | Anti-melanoma benzyl pyrimidine compound and preparation method and application thereof | 中国医科大学附属盛京医院 | 2024-09-20 | — | — | CN | claimed |
| CN-116391047-A | Mass spectrometry-based methods and kits for nucleic acid detection and disease diagnosis | YYZ医药科技有限公司 | 2023-07-04 | — | — | CN | claimed |
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | claimed |
| CN-109996804-B | Squalamine amide derivatives for the treatment of infections | 维克公司 | 2022-04-08 | — | — | CN | claimed |
| EP-3512865-B1 | ESTERS OF 3-POLYAMINE DERIVATIVES OF BILE ACIDS FOR THE TREATMENT OF INFECTIONS | VIRBAC (FR) | 2021-05-05 | — | — | EP | claimed |
| EP-3512864-B1 | AMIDE DERIVATIVES OF SQUALAMINE FOR THE TREATMENT OF INFECTIONS | VIRBAC (FR) | 2021-01-20 | — | — | EP | claimed |
| US-10543258-B2 | Antibacterial composition containing ADK protein as active ingredient, or composition for preventing or treating sepsis | KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION (KR) | 2020-01-28 | — | — | US | claimed |
| US-20190262362-A1 | AMIDE DERIVATIVES OF SQUALAMINE FOR THE TREATMENT OF INFECTIONS | VIRBAC (FR) | 2019-08-29 | — | — | US | claimed |
| US-20190255073-A1 | ESTERS OF 3-POLYAMINE DERIVATIVES OF BILE ACIDS FOR THE TREATMENT OF INFECTIONS | VIRBAC (FR) | 2019-08-22 | — | — | US | claimed |
| EP-0054756-B1 | ANTIBACTERIAL BENZYLPYRIMIDINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-07-23 | — | — | EP | claimed |
| EP-0032395-B1 | BENZYLPYRIMIDINES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-03-23 | — | — | EP | claimed |
| EP-0003212-B1 | 2.4-DIAMINO-5-BENZYLPYRIMIDINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-03-17 | — | — | EP | claimed |
| EP-0032395-A1 | Benzylpyrimidines | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-07-22 | — | — | EP | claimed |
| US-4279899-A | MICROBIOCIDES | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | claimed |
| US-4260602-A | FOR INHIBITING ALLERGIC REACTION TO DRUG | BURROUGHS WELLCOME CO. (US) | 1981-04-07 | — | — | US | claimed |
| US-4189581-A | BACTERICIDES, POTENTIATORS OF SULFA DRUGS | BASF AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | claimed |
| EP-0003212-A1 | 2.4-Diamino-5-benzylpyrimidines, pharmaceutical compositions containing them and their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-08-08 | — | — | EP | claimed |
| US-4137411-A | Preparation of 2,4-diamino-5-(4-amino-3,5-substituted-benzyl)-pyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1979-01-30 | — | — | US | claimed |
| EP-0000334-A1 | 2,4-Diamino-5-benzyl-pyrimidines, process for their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1979-01-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10543258-B2 | Antibacterial composition containing ADK protein as active ingredient, or composition for preventing or treating sepsis | ADK, AAK1, ADCK1 | CALM1 1626/4885TAAR1 3333/4885HSD17B10 3540/4885 |
| US-20190262362-A1 | AMIDE DERIVATIVES OF SQUALAMINE FOR THE TREATMENT OF INFECTIONS | SUCNR1, GLRA1, SRR | CALM1 1925/4885TAAR1 74/4885HSD17B10 1056/4885 |
| US-20190255073-A1 | ESTERS OF 3-POLYAMINE DERIVATIVES OF BILE ACIDS FOR THE TREATMENT OF INFECTIONS | GPBAR1, NR1H4, ESRRA | CALM1 2927/4885TAAR1 20/4885HSD17B10 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.