Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601414 | 0.80 | EGFR (0.44) | EGFRALDH1A1L3MBTL1POLBSGMS2 | |
| SCHEMBL4600204 | 0.80 | IRAK4 (0.44) | HDAC8EGFRALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4602183 | 0.79 | EGFR (0.47) | EGFRMAPTL3MBTL1SGMS2MRGPRX4 | |
| SCHEMBL4601601 | 0.76 | EGFR (0.47) | EGFRALDH1A1MAPTGAAKMT2A | |
| SCHEMBL4600130 | 0.75 | EGFR (0.47) | EGFRALDH1A1CYP1A2CYP2C9KMT2A | |
| SCHEMBL4601218 | 0.74 | MRGPRX4 (0.46) | EGFRALDH1A1MRGPRX4KMT2AKDM4E | |
| SCHEMBL4601033 | 0.73 | EGFR (0.44) | EGFRTHRBKDM4E | |
| SCHEMBL4600789 | 0.73 | HPGD (0.48) | ALDH1A1CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL4600628 | 0.72 | EGFR (0.47) | EGFRALDH1A1MAPTL3MBTL1GAA | |
| SCHEMBL4600843 | 0.71 | RAB9A (0.50) | EGFRALDH1A1MAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |