Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77703 | 0.82 | POLB (0.36) | POLBHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL39017 | 0.80 | POLB (0.34) | POLBHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL624908 | 0.80 | POLB (0.34) | POLBHTR1DGABBR2GABBR1 | |
| SCHEMBL5455454 | 0.78 | POLB (0.33) | POLBHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL624909 | 0.77 | GABBR2 (0.33) | POLBHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL7136246 | 0.74 | GABRA1 (0.43) | POLBHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL27974117 | 0.71 | POLB (0.55) | POLBHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL27489164 | 0.70 | POLB (0.48) | POLBHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL11357994 | 0.69 | POLB (0.46) | POLBHTR1DHTR1BGABRA1GABRB2 | |
| SCHEMBL28528734 | 0.69 | HSP90AA1 (0.42) | POLBHTR1DGABRA1GABRB2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130283834-A1 | PHENOL STABILIZERS FOR FLUOROOLEFINS | THE CHEMOURS COMPANY FC, LLC | 2013-10-31 | — | — | US | claimed |
| US-8535556-B2 | Compositions comprising iodotrifluoromethane and stabilizers | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-09-17 | — | — | US | claimed |
| US-8496846-B2 | Phenol stabilizers for fluoroolefins | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-07-30 | — | — | US | claimed |
| US-20120047925-A1 | PHENOL STABILIZERS FOR FLUOROOLEFINS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-01 | — | — | US | claimed |
| US-20110037017-A1 | COMPOSITIONS COMPRISING IODOTRIFLUOROMETHANE AND STABILIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-17 | — | — | US | claimed |
| US-20090288431-A1 | PHENOL STABILIZERS FOR FLUOROOLEFINS | THE CHEMOURS COMPANY FC, LLC | 2009-11-26 | — | — | US | claimed |
| WO-2007126760-A2 | COMPOSITIONS COMPRISING IODOTRIFLUOROMETHANE AND STABILIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-08 | — | — | WO | claimed |
| US-8815114-B2 | Phenol stabilizers for fluoroolefins | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-26 | — | — | US | disclosed |
| US-8663494-B2 | Terpene, terpenoid, and fullerene stabilizers for fluoroolefins | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-03-04 | — | — | US | disclosed |
| US-20130283834-A1 | PHENOL STABILIZERS FOR FLUOROOLEFINS | THE CHEMOURS COMPANY FC, LLC | 2013-10-31 | — | — | US | disclosed |
| US-8535556-B2 | Compositions comprising iodotrifluoromethane and stabilizers | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-09-17 | — | — | US | disclosed |
| US-8496846-B2 | Phenol stabilizers for fluoroolefins | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-07-30 | — | — | US | disclosed |
| US-8383004-B2 | Amine stabilizers for fluoroolefins | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-02-26 | — | — | US | disclosed |
| US-8101094-B2 | Terpene, terpenoid, and fullerene stabilizers for fluoroolefins | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110041530-A1 | AMINE STABILIZERS FOR FLUOROOLEFINS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 2011-02-24 | — | — | US | disclosed |
| US-20110037017-A1 | COMPOSITIONS COMPRISING IODOTRIFLUOROMETHANE AND STABILIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-17 | — | — | US | disclosed |
| US-20100288965-A1 | TERPENE, TERPENOID, AND FULLERENE STABILIZERS FOR FLUOROOLEFINS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-18 | — | — | US | disclosed |
| US-20090288431-A1 | PHENOL STABILIZERS FOR FLUOROOLEFINS | THE CHEMOURS COMPANY FC, LLC | 2009-11-26 | — | — | US | disclosed |
| EP-2069455-A1 | TERPENE, TERPENOID, AND FULLERENE STABILIZERS FOR FLUOROOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008027514-A1 | TERPENE, TERPENOID, AND FULLERENE STABILIZERS FOR FLUOROOLEFINS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100288965-A1 | TERPENE, TERPENOID, AND FULLERENE STABILIZERS FOR FLUOROOLEFINS | FNTA, FDPS, FNTB | POLB 3804/4885HTR1D 3245/4885HTR1B 4419/4885 |
| US-20110041530-A1 | AMINE STABILIZERS FOR FLUOROOLEFINS | AFF1, PFAS, FLNA | POLB 1036/4885HTR1D 269/4885HTR1B 608/4885 |
| US-20120047925-A1 | PHENOL STABILIZERS FOR FLUOROOLEFINS | HSF1, FLOT1, FOXK1 | POLB 1494/4885HTR1D 1847/4885HTR1B 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.