Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14881017 | 0.80 | MEN1 (0.54) | PLA2G7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3529574 | 0.75 | PLA2G7 (0.65) | PLA2G7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27700307 | 0.72 | EGFR (0.56) | PLA2G7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29740133 | 0.70 | GRM4 (0.51) | PLA2G7MEN1KMT2AALDH1A1SCN9A | |
| SCHEMBL2981886 | 0.70 | ALDH1A1 (0.61) | PLA2G7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3529772 | 0.69 | PLA2G7 (0.61) | PLA2G7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28474122 | 0.69 | PLA2G7 (0.60) | PLA2G7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8906815 | 0.68 | PLA2G7 (0.59) | PLA2G7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27630368 | 0.67 | PLA2G7 (0.55) | PLA2G7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20529581 | 0.66 | PLA2G7 (0.70) | PLA2G7NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004607-A2 | NEW COMPOUNDS | Novartis AG (CH) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007126957-A2 | NEW COMPOUNDS | NOVARTIS AG (CH) | 2007-11-08 | — | — | WO | disclosed |