Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328965 | 0.91 | KDM4E (0.55) | L3MBTL1TDP1KDM4EMAPTEGFR | |
| SCHEMBL2039160 | 0.89 | KDM4E (0.58) | L3MBTL1TDP1KDM4EMAPTRAB9A | |
| SCHEMBL8014661 | 0.84 | RXRA (0.61) | L3MBTL1TDP1KDM4EEGFRALDH1A1 | |
| SCHEMBL4601625 | 0.83 | EGFR (0.53) | L3MBTL1TDP1KDM4EMAPTRAB9A | |
| SCHEMBL2050621 | 0.82 | EGFR (0.56) | L3MBTL1MAPTRAB9AEGFRSMN1; SMN2 | |
| SCHEMBL29788043 | 0.82 | EGFR (0.56) | L3MBTL1MAPTRAB9AEGFRSMN1; SMN2 | |
| SCHEMBL20021919 | 0.81 | BCL9 (0.54) | KDM4EMAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL536427 | 0.79 | MAPT (0.59) | KDM4EMAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL27301114 | 0.78 | ADRB2 (0.63) | KDM4ERAB9AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL1389258 | 0.78 | ADRB2 (0.67) | KDM4ERAB9AALDH1A1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |