Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604364 | 0.89 | KDM4E (0.50) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 | |
| SCHEMBL4602884 | 0.81 | L3MBTL1 (0.52) | ALDH1A1KDM4EHTTLMNATSHR | |
| SCHEMBL4602793 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EHTT | |
| SCHEMBL1512564 | 0.78 | MEN1 (0.67) | ALDH1A1KDM4ELMNATSHRSMN1; SMN2 | |
| SCHEMBL4602273 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4EHTTLMNATSHR | |
| SCHEMBL28424017 | 0.76 | IDO1 (0.49) | ALDH1A1KDM4E | |
| SCHEMBL5519966 | 0.75 | ALDH1A1 (0.69) | ALDH1A1KDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL21650947 | 0.74 | HSD11B1 (0.63) | ALDH1A1KDM4ELMNATSHRSMN1; SMN2 | |
| SCHEMBL22164021 | 0.74 | LMNA (0.60) | ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL20328139 | 0.74 | LMNA (0.65) | ALDH1A1KDM4EHTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761520-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2008-07-09 | — | — | EP | disclosed |