Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15844791 | 0.87 | CA1 (0.54) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL2420908 | 0.85 | TSHR (0.44) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL6682827 | 0.83 | GABRA1 (0.63) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL16785950 | 0.79 | GABRA1 (0.52) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL5077373 | 0.79 | GABRA1 (0.47) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL4782428 | 0.78 | ESR1 (0.35) | GABRA1GABRB1GABRB2CA1CA2 | |
| Propane SCHEMBL28229965 | 0.77 | GABRA1 (0.46) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL8376286 | 0.76 | HSD17B10 (0.42) | THRATHRBCYP1A2CYP3A4TSHR | |
| SCHEMBL4644161 | 0.72 | GABRA1 (0.78) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL15539232 | 0.72 | GABRA1 (0.44) | GABRA1GABRB1GABRB2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414276-A1 | INHERENTLY HEALING POLYCARBONATE RESINS | SABIC Global Technologies B.V. (NL) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017137951-A1 | INHERENTLY HEALING POLYCARBONATE RESINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-08-17 | — | — | WO | disclosed |
| CN-101472994-A | Polycarbonate compositions and articles formed therefrom | GEN ELECTRIC (NL) | 2009-07-01 | — | — | CN | disclosed |
| EP-1751211-B1 | METHOD FOR PREPARING A POLYCARBONATE OLIGOMER MIXTURE AT LOW TEMPERATURE FOR MANUFACTURING POLYCARBONATE | GEN ELECTRIC (US) | 2008-04-30 | — | — | EP | disclosed |
| CN-1383450-A | Antibody molecule with specificity to human tumor necrosis factor alpha and application thereof | CELLTECH R&D LTD (GB) | 2002-12-04 | — | — | CN | disclosed |