SCHEMBL2420908

SCHEMBL2420908

CCC(c1cc(Br)c(O)c(Br)c1)c1cc(Br)c(O)c(Br)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
CYP3A4 P08684 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
HIF1A Q16665 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TTR P02766 2/20 0.41
ALOX15 P16050 2/20 0.41
ALOX12 P18054 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
CASP1 P29466 1/20 0.41
RECQL P46063 1/20 0.41
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
CYP2C19 P33261 2/20 0.39
CYP2C9 P11712 2/20 0.38
HKDC1 Q2TB90 1/20 0.37
ESR1 P03372 1/20 0.37
MEN1 O00255 1/20 0.37
ALB P02768 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4782428 0.88 ESR1 (0.35) TSHRCYP3A4TDP1HIF1AHSD17B10
SCHEMBL8376286 0.86 HSD17B10 (0.42) TSHRCYP3A4TDP1HIF1AHSD17B10
SCHEMBL4603027 0.85 GABRA1 (0.47) TSHRCYP3A4HIF1AHPGDCYP2C19
SCHEMBL6553806 0.83 TSHR (0.41) TSHRCYP3A4TDP1HIF1AHSD17B10
SCHEMBL1596341 0.81 TSHR (0.48) TSHRCYP3A4TDP1HIF1AHSD17B10
SCHEMBL1596252 0.81 TSHR (0.48) TSHRCYP3A4TDP1HIF1AHSD17B10
SCHEMBL4799655 0.80 CRHBP (0.46) TSHRCYP3A4TDP1ALDH1A1CRHBP
SCHEMBL13920802 0.80 ALDH1A1 (0.44) TSHRCYP3A4TDP1HIF1AHSD17B10
SCHEMBL234097 0.79 ALDH1A1 (0.36) TSHRCYP3A4TDP1HIF1AALDH1A1
SCHEMBL1595906 0.77 TSHR (0.44) TSHRCYP3A4TDP1HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105899577-B Copolycarbonate and composition comprising the Copolycarbonate LG化学株式会社 2019-08-16 CN claimed
CN-109563336-A Polycarbonate compositions and articles comprising the same 株式会社LG化学 2019-04-02 CN claimed
CN-107108876-B Copolycarbonate and composition containing same 株式会社LG化学 2019-03-08 CN claimed
CN-105899607-B Poly carbonate resin composition LG化学株式会社 2018-11-16 CN claimed
CN-106715527-B Copolycarbonate resin and method for producing same 株式会社LG化学 2018-11-13 CN claimed
CN-105899575-B Copolycarbonate and composition containing same LG化学株式会社 2018-07-24 CN claimed
CN-105899573-B Copolycarbonate and composition comprising the Copolycarbonate LG化学株式会社 2018-07-13 CN claimed
EP-0694035-B1 WATER-SOLUBLE CAMPTOTHECIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS PHARMACIA ITALIA SPA (IT) 2002-07-17 EP claimed
US-5595789-A CROSSLINKAKLE RESIN COATING ON SUBSTRATES FOR IMPACT STRENGTH, HEAT DEFLECTION AND DIMENSIONAL STABILITY BAYER AG (DE) 1997-01-21 US claimed
EP-0187640-B1 FLAME RETARDANT POLYCARBONATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1989-10-18 EP claimed
US-4751260-A HALOGEN-CONTAINING POLYCARBONATES, STYRENE-(METH)-ACRYLONITRILE COPOLYMERS, TETRAFLUOROETHYLENE POLYMERS, PHOSPHORUS COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1988-06-14 US claimed
US-4731405-A Thermoplastic moulding materials with high tracking resistance BAYER AKTIENGESELLSCHAFT (DE) 1988-03-15 US claimed
EP-0187640-A1 Flame retardant polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1986-07-16 EP claimed
US-4579896-A CONTAINING BIS CYCLI CARBONATE AND EITHER SULFONIC ACID SALT DERIVATIVES OR HALOGEN-CONTAINING COMPOUNDS GENERAL ELECTRIC COMPANY (US) 1986-04-01 US claimed
US-12617753-B2 Urea derivatives and their use as curatives and curative accelerators for resin systems HEXCEL COMPOSITES LIMITED (GB) 2026-05-05 US disclosed
EP-3959217-B1 IMPROVEMENTS IN OR RELATING TO CURATIVES HEXCEL COMPOSITES LTD (GB) 2025-10-15 EP disclosed
US-12371547-B2 Inorganic-reinforced thermoplastic polyester resin composition and molded products comprising same TOYOBO MC CORPORATION (JP) 2025-07-29 US disclosed
US-4322521-A Process for producing halogenated aromatic polyesters CELANESE CORPORATION (US) 1982-03-30 US disclosed
US-4316981-A Polycarbonate transesterification GENERAL ELECTRIC COMPANY (US) 1982-02-23 US disclosed
US-4102859-A PHOSPHOROUS ACID ESTERS WITH OXETANE COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1978-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617753-B2 Urea derivatives and their use as curatives and curative accelerators for resin systems UTS2R, UPP1, XDH TSHR 3401/4885CYP3A4 3441/4885TDP1 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.